Susceptibilidad de enterobacterias a piperacilina/tazobactam en un hospital pediátrico de Chile
Author
dc.contributor.author
Rojas de la Vega, Juan
Author
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Benadof, Dona
Author
dc.contributor.author
Veas, Abigail
Author
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Acuña, Mirta
Admission date
dc.date.accessioned
2018-05-31T17:25:41Z
Available date
dc.date.available
2018-05-31T17:25:41Z
Publication date
dc.date.issued
2017
Cita de ítem
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Rev Chilena Infectol 2017; 34 (6): 563-569
es_ES
Identifier
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0717-6341
Identifier
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https://repositorio.uchile.cl/handle/2250/148428
Abstract
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Introduction: Enterobacteriaceae are a group of gram-negative rods that can cause serious infections in humans.
A susceptibility in Klebsiella pneumoniae of 79.4% to piperacillin/tazobactam (PIP/TAZO) is reported in
pediatric hospitals in Chile. There is no published data published to date regarding PIP/TAZO susceptibility to
other Enterobacteriaceae species in this population. Aim: To measure the in vitro PIP/TAZO susceptibility in
Enterobacteriaceae isolates from patients in a pediatric hospital in Chile. Methods: Descriptive and prospective
study of Enterobacteriaceae positive cultures from patients assisting to the “Hospital de niños Roberto del Río”
(HRRIO) between January 2013 and August 2014. PIP/TAZO susceptibility was established by gradient diffusion
method (E-test®) according to the 2014 CLSI standards. Results: 163 cases were included. The average age was 4
years and 15 days. 70.6% were female. 79.7% of samples were urine cultures. PIP/TAZO susceptibility in Enterobacteriaceae
was 95.1% (n = 155). The intermediate susceptibility was 1.8% (n = 3). Discussion: The isolates
studied present high susceptibility to PIP/TAZO. This finding could be explained by the fact that this population
has not been exposed to this antimicrobial therapy and also the low rates for ESBL in pediatric infections.