Olfactory transduction in ciliated receptor neurons of the Cabinza grunt, Isacia conceptionis (teleostei: haemulidae)
Author
dc.contributor.author
Schmachtenberg, Oliver
Author
dc.contributor.author
Bacigalupo Vicuña, Juan
Admission date
dc.date.accessioned
2018-12-20T14:10:45Z
Available date
dc.date.available
2018-12-20T14:10:45Z
Publication date
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2004
Cita de ítem
dc.identifier.citation
European Journal of Neuroscience, Volumen 20, Issue 12, 2018, Pages 3378-3386
Identifier
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0953816X
Identifier
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10.1111/j.1460-9568.2004.03825.x
Identifier
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https://repositorio.uchile.cl/handle/2250/154417
Abstract
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The ciliated receptor neurons of fish olfactory organs are thought to transduce amino acids through a cAMP-dependent transduction pathway, but direct physiological evidence for this hypothesis remains scarce and is confined to catfish and trout. We investigated olfactory transduction in a marine fish, the Cabinza grunt Isacia conceptionis (Perciformes, Teleostei). The olfactory epithelium was characterized using light and electron microscopy, and isolated ciliated receptor neurons were recorded with the perforated patch-clamp technique. Cells were stimulated with puffer pipettes containing amino acid odourants, IBMX plus forskolin or 8bromo-cAMP. All three stimuli triggered transient inward currents at a holding potential of -70 mV and responses with outward-rectifying current-voltage relationships. The characteristics of the transduction currents induced by each stimulus were similar across cells and indistinguishable within the same cell, supporting the hypothesis of a cAMP pathway m