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Authordc.contributor.authorGuerrero Bosagna, Carlos 
Authordc.contributor.authorSabat Kirkwood, Alejandro Pablo 
Authordc.contributor.authorValladares Boasi, Luis 
Cita de ítemdc.identifier.citationEvolution and Development, Volumen 7, Issue 4, 2018, Pages 341-350
Abstractdc.description.abstractDNA methylation is one of the epigenetic and hereditary mechanisms regulating genetic expression in mammalian cells. In this review, we propose how certain natural agents, through their dietary consumption, could induce changes in physiological aspects in mammalian mothers, leading to alterations in DNA methylation patterns of the developing fetus and to the emergence of new phenotypes and evolutionary change. Nevertheless, we hypothesize that this process would require (i) certain key periods in the ontogeny of the organism where the environmental stimuli could produce effects, (ii) particular environmental agents as such stimuli, and (iii) that a genomic persistent change be consequently produced in a population. Depending on the persistence of the environmental stimuli and on whether the affected genes are imprinted genes, induced changes in DNA methylation patterns could become persistent. Moreover, some fragments could be more frequently methylated than others over several generat
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourceEvolution and Development
Keywordsdc.subjectEcology, Evolution, Behavior and Systematics
Keywordsdc.subjectDevelopmental Biology
Títulodc.titleEnvironmental signaling and evolutionary change: Can exposure of pregnant mammals to environmental estrogens lead to epigenetically induced evolutionary changes in embryos?
Document typedc.typeArtículo de revista
Indexationuchile.indexArtículo de publicación SCOPUS

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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile