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Authordc.contributor.authorZúñiga, Alejandro 
Authordc.contributor.authorHödar Quiroga, Christian 
Authordc.contributor.authorHanna, Patricia 
Authordc.contributor.authorIbáñez, Freddy 
Authordc.contributor.authorMoreno, Pablo 
Authordc.contributor.authorPulgar Tejo, Rodrigo 
Authordc.contributor.authorPastenes, Luis 
Authordc.contributor.authorGonzález, Mauricio 
Authordc.contributor.authorCambiazo Ayala, Verónica 
Cita de ítemdc.identifier.citationBMC Biology, Volumen 7,
Abstractdc.description.abstractBackground: Morphogenetic events that shape the Drosophila melanogaster embryo are tightly controlled by a genetic program in which specific sets of genes are up-regulated. We used a suppressive subtractive hybridization procedure to identify a group of developmentally regulated genes during early stages of D. melanogaster embryogenesis. We studied the spatiotemporal activity of these genes in five different intervals covering 12 stages of embryogenesis. Results: Microarrays were constructed to confirm induction of expression and to determine the temporal profile of isolated subtracted cDNAs during embryo development. We identified a set of 118 genes whose expression levels increased significantly in at least one developmental interval compared with a reference interval. Of these genes, 53% had a phenotype and/or molecular function reported in the literature, whereas 47% were essentially uncharacterized. Clustering analysis revealed demarcated transcript groups with maximum gene activi
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 Chile
Link to Licensedc.rights.uri
Sourcedc.sourceBMC Biology
Keywordsdc.subjectStructural Biology
Keywordsdc.subjectEcology, Evolution, Behavior and Systematics
Keywordsdc.subjectBiochemistry, Genetics and Molecular Biology (all)
Keywordsdc.subjectAgricultural and Biological Sciences (all)
Keywordsdc.subjectPlant Science
Keywordsdc.subjectDevelopmental Biology
Keywordsdc.subjectCell Biology
Títulodc.titleGenes encoding novel secreted and transmembrane proteins are temporally and spatially regulated during Drosophila melanogaster embryogenesis
Document typedc.typeArtículo de revista
Indexationuchile.indexArtículo de publicación SCOPUS

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Attribution-NonCommercial-NoDerivs 3.0 Chile
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile