A selective fluorescent probe for the detection of mercury (II) in aqueous media and its applications in living cells
| Author | dc.contributor.author | García Beltrán, Olimpo | |
| Author | dc.contributor.author | Mena, Natalia | |
| Author | dc.contributor.author | Berríos, Tania A. | |
| Author | dc.contributor.author | Castro, Enrique A. | |
| Author | dc.contributor.author | Cassels Niven, Bruce | |
| Author | dc.contributor.author | Núñez González, Marco | |
| Author | dc.contributor.author | Aliaga, Margarita E. | |
| Admission date | dc.date.accessioned | 2018-12-20T14:13:50Z | |
| Available date | dc.date.available | 2018-12-20T14:13:50Z | |
| Publication date | dc.date.issued | 2012 | |
| Cita de ítem | dc.identifier.citation | Tetrahedron Letters, Volumen 53, Issue 48, 2018, Pages 6598-6601 | |
| Identifier | dc.identifier.issn | 00404039 | |
| Identifier | dc.identifier.issn | 18733581 | |
| Identifier | dc.identifier.other | 10.1016/j.tetlet.2012.09.111 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/154979 | |
| Abstract | dc.description.abstract | In this Letter we present a new probe, 2-amino-3-hydroxy-2-(hydroxymethyl) propyl 2-(7-hydroxy-2-oxo-2H-chromen-4-yl)acetate (PMR), which can reversibly detect mercuric ions (Hg 2+) in HEPES buffer under physiological conditions. Possible interference with other analytes was examined. PMR displays a highly selective decrease of its fluorescence at 460 nm when it reacts with Hg 2+. Interestingly, the probe can also be used as a fluorescent turn-on sensor for biologically relevant thiols such as glutathione and cysteine. PMR can be used to determine mercury in living cells. © 2012 Elsevier Ltd. All rights reserved. | |
| Lenguage | dc.language.iso | en | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | Tetrahedron Letters | |
| Keywords | dc.subject | Biothiols | |
| Keywords | dc.subject | Coumarin derivatives | |
| Keywords | dc.subject | Fluorescent probe | |
| Keywords | dc.subject | Hg2+-selectivity | |
| Título | dc.title | A selective fluorescent probe for the detection of mercury (II) in aqueous media and its applications in living cells | |
| Document type | dc.type | Artículo de revista | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile