Peroxisomal and microsomal fatty acid oxidation in liver of rats after chronic ethanol consumption
| Author | dc.contributor.author | Orellana, Myriam | |
| Author | dc.contributor.author | Rodrigo Salinas, Ramón | |
| Author | dc.contributor.author | Valdés, Elena | |
| Admission date | dc.date.accessioned | 2018-12-20T14:32:24Z | |
| Available date | dc.date.available | 2018-12-20T14:32:24Z | |
| Publication date | dc.date.issued | 1998 | |
| Cita de ítem | dc.identifier.citation | General Pharmacology, Volumen 31, Issue 5, 2018, Pages 817-820 | |
| Identifier | dc.identifier.issn | 03063623 | |
| Identifier | dc.identifier.other | 10.1016/S0306-3623(98)00054-8 | |
| Identifier | dc.identifier.uri | https://repositorio.uchile.cl/handle/2250/156377 | |
| Abstract | dc.description.abstract | 1. Microsomal P450 and peroxisomal fatty acid oxidation activities were studied in liver of rats after long-term ethanol consumption. 2. Ethanol increased the microsomal lauric acid ω-hydroxylation and the aminopyrine N-demethylation catalyzed by cytochrome P450. 3. Ethanol increased peroxisomal β-oxidation of palmitoyl CoA and catalase activity in liver. 4. Both microsomal and peroxisomal activities behaved in a coordinate way in the liver of rats with long-term ethanol consumption. 5. These results would support a role of microsomal ω-hydroxylation and peroxisomal β-oxidation of fatty acids in an extramitochondrial pathway of lipid oxidation in the liver. Copyright (C) 1998 Elsevier Science Inc. | |
| Lenguage | dc.language.iso | en | |
| Type of license | dc.rights | Attribution-NonCommercial-NoDerivs 3.0 Chile | |
| Link to License | dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/3.0/cl/ | |
| Source | dc.source | General Pharmacology | |
| Keywords | dc.subject | Aminopyrine | |
| Keywords | dc.subject | Catalase | |
| Keywords | dc.subject | Cytochrome P450 | |
| Keywords | dc.subject | Ethanol | |
| Keywords | dc.subject | Lauric acid | |
| Keywords | dc.subject | Peroxisomal fatty acid oxidation | |
| Título | dc.title | Peroxisomal and microsomal fatty acid oxidation in liver of rats after chronic ethanol consumption | |
| Document type | dc.type | Artículo de revista | |
| Cataloguer | uchile.catalogador | SCOPUS | |
| Indexation | uchile.index | Artículo de publicación SCOPUS | |
| uchile.cosecha | uchile.cosecha | SI |
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Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 Chile