Antimicrobial Activity of Natural 2-Benzoxazolinones and Related Derivatives
Author
dc.contributor.author
Bravo, Héctor R.
Author
dc.contributor.author
Copaja, Sylvia V.
Author
dc.contributor.author
Lazo, Waldo
Admission date
dc.date.accessioned
2018-12-20T14:39:20Z
Available date
dc.date.available
2018-12-20T14:39:20Z
Publication date
dc.date.issued
1997
Cita de ítem
dc.identifier.citation
Journal of Agricultural and Food Chemistry, Volumen 45, Issue 8, 2018, Pages 3255-3257
Identifier
dc.identifier.issn
00218561
Identifier
dc.identifier.other
10.1021/jf9608581
Identifier
dc.identifier.uri
https://repositorio.uchile.cl/handle/2250/156878
Abstract
dc.description.abstract
Natural 2-benzoxazolinones BOA and MBOA and related synthetic derivatives inhibited the growth of Staphylococcus aureus, Escherichia coli, and Candida albicans. Both the electrophilic character of the nitrogen atom of the heterocyclic ring and the lipophilic character of the substituents of the aromatic ring are involved in the antifungal activity. These two effects are evaluated by the shift of the infrared N-H frequencies and by the correlation between the antifungal activity and the π parameter, respectively.