Voltammetric behaviour of ketorolac and its HPLC-EC determination in tablets
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Squella Serrano, Juan
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Voltammetric behaviour of ketorolac and its HPLC-EC determination in tablets
Abstract
Ketorolac is an antiinflammatory-analgesic agent that is oxidizable at the glassy carbon electrode. The voltammetric oxidation produces two well resolved pH-dependent peaks, that are overlapped at pH>10. Using this voltammetric response a HPLC procedure with electrochemical detection in order to quantify ketorolac in pharmaceutical dosage forms is presented. Furthermore comparative methods using UV spectrophotometry and HPLC with photodiode array detector were used.
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URI: https://repositorio.uchile.cl/handle/2250/158008
DOI: 10.1080/00032719708001801
ISSN: 00032719
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Analytical Letters, Volumen 30, Issue 3, 2018, Pages 553-564
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