Acanthosis nigricans as an indicator of insulin resistance in Chilean adult population Acantosis nigricans como un indicador deinsulinoresistencia en poblacion Chilena adulta
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Pinheiro, A. C.
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Acanthosis nigricans as an indicator of insulin resistance in Chilean adult population Acantosis nigricans como un indicador deinsulinoresistencia en poblacion Chilena adulta
Abstract
Background: Insulin resistance (IR) is associated with a higher risk of multiple diseases and its early detection would allow to minimize the associated risk; the presence of acanthosis nigricans (AN) it's associated to the presence of IR. Objective: To evaluate the sensibility and specificity of AN to diagnose IR in a group of Chilean patients. Methods: We designed a cross-sectional study and it was included subjects that were attended at the Center for the Attention of Metabolic Diseases at the Faculty of Medicine, University of Chile. Sixty subjects (18-60 years age) were included. It was determined BMI and diagnosed AN and skin phototype; blood samples were taken and calculated the HOMA-IR. The normality of the variables where analyzed by Kolmogorov-Smirnov test. There were used x 2 and the diagnostic concordance between AN and IR was determined using the Kappa index and Pearson's correlation. Sensibility, specificity, positive and negative predictive value were calculated and acce
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URI: https://repositorio.uchile.cl/handle/2250/165333
DOI: 10.3305/nh.2011.26.5.4955
ISSN: 02121611
16995198
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Nutricion Hospitalaria, Volumen 26, Issue 5, 2018, Pages 940-944
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