Terapia de reperfusión en infarto agudo al miocardio. Comparación entre trombolisis endovenosa y angioplastía coronaria
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2011Metadata
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Ugalde, Héctor
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Terapia de reperfusión en infarto agudo al miocardio. Comparación entre
trombolisis endovenosa y angioplastía
coronaria
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Abstract
Background: Primary angioplasty is superior to intravenous thrombolysis as
reperfusion therapy for acute myocardial infarction. Aim: To compare the results of
available reperfusion strategies for initial management of acute myocardial infarction
during hospitalization and 5 years follow up. Patients and Methods: Historical
cohort study from a prospective registry of patients admitted with acute myocardial
infarction to our center. Patients treated with primary angioplasty were identifi ed and
were then matched by age, sex and date of event with patients treated with thrombolysis.
The clinical outcomes were compared including hospitalization and 5-years
follow-up. Results: From March 1993 to August 2001, 98 patients were treated with
primary angioplasty and matched with 98 thrombolyzed patients. The groups were
comparable. Compared to thrombolysis, angioplasty had a higher success rate (68 and
91% respectively), resulted in less complications and reduced mortality (11 and 2%
respectively), required less revascularization procedures and shorter hospital stay (17
and 13 days, respectively). During the follow-up of survivors, no differences in events or
additional mortality were detected at 1 or 5 years. Conclusions: Primary angioplasty
is superior as treatment in terms of achieving success and reducing mortality during
hospitalization. Evolution after hospitalization is independent of initial therapy.
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Artículo de publicación SCOPUS
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URI: https://repositorio.uchile.cl/handle/2250/165469
DOI: 10.4067/S0034-98872011001100002
ISSN: 00349887
07176163
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Rev Med Chile 2011; 139: 1396-1402
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