Failure of cotrimoxazole prophylaxis for pneumocystis jiroveci pneumonia with concomitant use of leucovorin. case report Falla de la profilaxis con cotrimoxazol para la neumonía por pneumocystis jiroveci con el uso concomitante de leucovorina. reporte de

Abstract

The concomitant use of leucovorin and cotrimoxazole in PCP can lead to therapeutic failure and increased risk of death due to antagonism. It is important to keep this possible antagonistic interaction in mind even during prophylaxis. This paper presents a case with this failure outcome.