Effects of smoking on plasma antimüllerian hormone concentrations among infertile women El hábito de fumar se asocia a baja concentración plasmática de hormona antimülleriana en mujeres infértiles
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2013Metadata
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Fuentes, Ariel
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Effects of smoking on plasma antimüllerian hormone concentrations among infertile women El hábito de fumar se asocia a baja concentración plasmática de hormona antimülleriana en mujeres infértiles
Abstract
Background: Smoking may hamper female fertility, probably modifying ovarian reserve. Antimüllerian hormone (AMH) is an accurate marker for ovarian reserve. Aim: To look for an association between smoking status and plasma AMH concentration. Patients and Methods: A cohort of 141 infertile women in a university setting in Santiago, Chile was studied. Demographic and smoking data, including the number of cigarettes smoked during the last week, were collected. A blood sample was obtained and kept frozen until determination of AMH by ELISA and follicle stimulating hormone (FSH) and estradiol at day three of the menstrual cycle, by radioimmunoanalysis. Results: Thirty two participants smoked (23%). There were no significant differences in age, parity, body mass index, causes of infertility and day three FSH and estradiol between smokers and nonsmokers. According to a regression analysis, there was a significant decrease in AMH concentration with age and active cigarette smoking. A drop in AM
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URI: https://repositorio.uchile.cl/handle/2250/165994
DOI: 10.4067/S0034-98872013000100003
ISSN: 00349887
07176163
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Revista Medica de Chile, Volumen 141, Issue 1, 2018, Pages 23-27
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