Survival of patients with duchenne muscular dystrophy Sobrevida de pacientes con distrofia muscular de duchenne

Abstract

© 2018, Sociedad Chilena de Pediatria. All rights reserved. Introduction: Duchenne muscular dystrophy (DMD) leads to a progressive deterioration of the muscle function and premature death. There are no longitudinal studies on the course of this pathology in Chile. Objective: To determine survival between the years 1993-2013, divided into two periods (1993-2002 and 2003-2013), and the effect of social determinants in patients with DMD admitted in Teleton Institutes of Chile (TI). Patients and Method:Prospective follow-up study in a clinical series of 462 patients with DMD. The information was obtained by searching for patients with DMD in OLAP cube (Online Analytical Processing). From the clinical records of the TI of Santiago, the variables corresponding to the diagnostic method, stage of DMD described in terms of muscle deterioration and function according to Swinyard classification were recorded; existence and type of tests that conclude the diagnosis and, in the cases reported, the