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Pemphigus-like eruption as a complication of molluscum contagiosum treatment with imiquimod in a 5-year-old girl

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2020
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Zhong, Connie S.
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Pemphigus-like eruption as a complication of molluscum contagiosum treatment with imiquimod in a 5-year-old girl
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  • Zhong, Connie S.;
  • Hasbún, Maria Trinidad;
  • Jones, Krystal M.;
  • Schmidt, Birgitta A. R.;
  • Hussain, Sadaf H.;
Abstract
Pemphigus and pemphigus-like reactions can be triggered by a variety of medications including topical therapies, such as imiquimod. While the association between imiquimod and pemphigus-like reactions has been reported in adults, this is the first report of a generalized reaction beyond the site of imiquimod application in a child. The mechanism by which this occurs may be through a unique pathway, separate from the classic antibody-mediated pathway. Our patient had a full recovery without recurrence after cessation of the inciting drug.
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URI: https://repositorio.uchile.cl/handle/2250/174864
DOI: 10.1111/pde.14115
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Pediatric Dermatology Volumen: 37 Número: 2 Páginas: 379-380
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