Show simple item record

Authordc.contributor.authorPino, José Luis
Authordc.contributor.authorMujica, Verónica
Authordc.contributor.authorArredondo Olguín, Miguel Armando
Cita de ítemdc.identifier.citationJournal of Functional Foods 77 (2021) 104311es_ES
Abstractdc.description.abstractThere is a growing interest in the use of functional foods. Studies indicate the contribution of β-glucans to glycemic control, but few have evaluated integrally the effect of this soluble dietary fiber on appetite-regulating hormones and microbiota in type-2 diabetes (T2D). We analyzed the effect of enriching a normal diet with oat β-glucan in thirty-seven T2D subjects. For 12 weeks, subjects consumed daily oat β-glucan or microcrystalline cellulose as control (5 g/day). We determined fasting glucose, C-peptide, insulin, HOMA, HbA1c, lipid profile, ghrelin, leptin, GLP-1, PYY, caloric intake, and intestinal microbiota. HbA1c decreased in the β-glucan group. Insulin, C-peptide and HOMA, Lactobacillus spp, and Butyrate-producing bacteria decreased in the β-glucan group (p < 0.05). Leptin (p < 0.05), GLP-1 (p < 0.01) and PYY (p < 0.001) were different between groups. The intake of 5 g/oat β-glucan for 12 weeks can help improve glycemic control, increase the feeling of satiety, and promote changes in the gut microbiota profile.es_ES
Patrocinadordc.description.sponsorshipMicronutrient Laboratory, Human Nutrition Unit, Institute of Nutrition and Food Technology (INTA), Universidad de Chilees_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
Link to Licensedc.rights.uri*
Sourcedc.sourceJournal of Functional Foodses_ES
Keywordsdc.subjectType-2 diabetes mellituses_ES
Keywordsdc.subjectDietary fiberes_ES
Keywordsdc.subjectGut hormoneses_ES
Títulodc.titleEffect of dietary supplementation with oat beta-glucan for 3 months in subjects with type 2 diabetes: A randomized, double-blind, controlled clinical triales_ES
Document typedc.typeArtículo de revistaes_ES
dc.description.versiondc.description.versionVersión publicada - versión final del editores_ES
dcterms.accessRightsdcterms.accessRightsAcceso abiertoes_ES
Indexationuchile.indexArtículo de publícación WoSes_ES
Indexationuchile.indexArtículo de publicación SCOPUSes_ES

Files in this item


This item appears in the following Collection(s)

Show simple item record

Attribution-NonCommercial-NoDerivs 3.0 United States
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 United States