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Authordc.contributor.authorDres, Martin
Authordc.contributor.authorSimilowski, Thomas
Authordc.contributor.authorGoligher, Ewan C.
Authordc.contributor.authorPham, Tai
Authordc.contributor.authorSergenyuk, Liliya
Authordc.contributor.authorTelias, Irene
Authordc.contributor.authorGrieco, Domenico Luca
Authordc.contributor.authorOuechani, Wissale
Authordc.contributor.authorJunhasavasdikul, Detajin
Authordc.contributor.authorSklar, Michael C.
Authordc.contributor.authorDamiani, L. Felipe
Authordc.contributor.authorMelo, Luana
Authordc.contributor.authorSantis, César
Authordc.contributor.authorDegravi, Lauriane
Authordc.contributor.authorDecavele, Maxens
Authordc.contributor.authorBrochard, Laurent
Authordc.contributor.authorDemoule, Alexandre
Admission datedc.date.accessioned2022-04-19T16:03:59Z
Available datedc.date.available2022-04-19T16:03:59Z
Publication datedc.date.issued2021
Cita de ítemdc.identifier.citationEuropean Respiratory Journal Volume 58 Issue 5 Article Number 2100002 Nov 1 2021es_ES
Identifierdc.identifier.other10.1183/13993003.00002-2021
Identifierdc.identifier.urihttps://repositorio.uchile.cl/handle/2250/184961
Abstractdc.description.abstractBackground This study investigated dyspnoea intensity and respiratory muscle ultrasound early after extubation to predict extubation failure. Methods The study was conducted prospectively in two intensive care units in France and Canada. Patients intubated for at least 48 h were studied within 2 h after an extubation following a successful spontaneous breathing trial. Dyspnoea was evaluated by a dyspnoea visual analogue scale (Dyspnoea-VAS) ranging from 0 to 10 and the Intensive Care Respiratory Distress Observational Scale (IC-RDOS). The ultrasound thickening fraction of the parasternal intercostal and the diaphragm was measured; limb muscle strength was evaluated using the Medical Research Council (MRC) score (range 0–60). Results Extubation failure occurred in 21 out of 122 enrolled patients (17%). The median (interquartile range (IQR)) Dyspnoea-VAS and IC-RDOS were higher in patients with extubation failure versus success: 7 (4–9) versus 3 (1–5) (p<0.001) and 3.7 (1.8–5.8) versus 1.7 (1.5–2.1) (p<0.001), respectively. The median (IQR) ratio of parasternal intercostal muscle to diaphragm thickening fraction was significantly higher and MRC was lower in patients with extubation failure compared with extubation success: 0.9 (0.4–2.1) versus 0.3 (0.2–0.5) (p<0.001) and 45 (36–50) versus 52 (44–60) (p=0.012), respectively. The thickening fraction of the parasternal intercostal and its ratio to diaphragm thickening showed the highest area under the receiver operating characteristic curve (AUC) for an early prediction of extubation failure (0.81). AUCs of Dyspnoea-VAS and IC-RDOS reached 0.78 and 0.74, respectively. Conclusions Respiratory muscle ultrasound and dyspnoea measured within 2 h after extubation predict subsequent extubation failure.es_ES
Patrocinadordc.description.sponsorshipFrench Intensive Care Society European Respiratory Society 2015 Bernhard Drager Award for Advanced Treatment of ARF of the European Society of Intensive Care Medicine Assistance Publique Hopitaux de Paris Fondation pour la Recherche Medicale FDM 20150734498 Mitacs Globalink Sorbonne Universiteses_ES
Lenguagedc.language.isoenes_ES
Publisherdc.publisherEuropean Respiratory Soces_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
Link to Licensedc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/*
Sourcedc.sourceEuropean Respiratory Journales_ES
Keywordsdc.subjectIntensive-care-unites_ES
Keywordsdc.subjectMechanical ventilationes_ES
Keywordsdc.subjectAcute exacerbationses_ES
Keywordsdc.subjectObservation scaleses_ES
Keywordsdc.subjectSelf-reportes_ES
Keywordsdc.subjectRib cagees_ES
Keywordsdc.subjectBreathlessnesses_ES
Keywordsdc.subjectReintubationes_ES
Keywordsdc.subjectManagementes_ES
Keywordsdc.subjectMortalityes_ES
Títulodc.titleDyspnoea and respiratory muscle ultrasound to predict extubation failurees_ES
Document typedc.typeArtículo de revistaes_ES
dc.description.versiondc.description.versionVersión publicada - versión final del editores_ES
dcterms.accessRightsdcterms.accessRightsAcceso abiertoes_ES
Catalogueruchile.catalogadorcrbes_ES
Indexationuchile.indexArtículo de publícación WoSes_ES


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Attribution-NonCommercial-NoDerivs 3.0 United States
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 United States