National Health and Medical Research Council (NHMRC) of Australia 1037746 1156093 1153439 Ministry of Health, Italy Ministry of Health Italy - Ricerca Finalizzata (MOH-RF) RF-2016-02362405 Progetti di Rilevante Interesse Nazionale program of the Ministry of Education, University and Research 2017SNW5MB EU Joint Programme-Neurodegenerative Disease Research - Italian Ministry of Education, University and Research Ministry of Education, Universities and Research (MIUR) Netherlands ALS Foundation E. von Behring Chair for Neuromuscular and Neurodegenerative Disorders ALS Liga Belgie KU Leuven fund 'Een Hart voor ALS' KU Leuven fund 'Laeversfonds voor ALS Onderzoek' KU Leuven fund 'Valery Perrier Race against ALS Fund' NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust NIHR202421 General Electric EU Joint Programme-Neurodegenerative Disease Research (JPND) project UK Research & Innovation (UKRI) Medical Research Council UK (MRC) MR/L501529/1 MR/R024804/1 UK Research & Innovation (UKRI) Economic & Social Research Council (ESRC) ES/L008238/1 Motor Neurone Disease Association

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