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Authordc.contributor.authorMedenica, Sanja
Authordc.contributor.authorSpoltore, María Elena
Authordc.contributor.authorOrmazábal Leiva, Paulina Fernanda
Authordc.contributor.authorMarina, Ljiljana V.
Authordc.contributor.authorSojatv, Antoan Stefan
Authordc.contributor.authorFaggiano, Antongiulio
Authordc.contributor.authorGnessi, Lucio
Authordc.contributor.authorMazzilli, Rossella
Authordc.contributor.authorWatanabe, Mikiko
Cita de ítemdc.identifier.citationClinical Endocrinology. 2023;98:141–152es_ES
Abstractdc.description.abstractObesity is an epidemic that has led to a rise in the incidence of many comorbidities: among others, reduced fertility is often under-evaluated in clinical practice. The mechanisms underlying the link between reduced fertility and obesity are numerous, with insulin resistance, hyperglycaemia and the frequent coexistence of polycystic ovary syndrome being the most acknowledged. However, several other factors concur, such as gut microbiome alterations, low-grade chronic inflammation and oxidative stress. Not only do women with obesity take longer to conceive, but in vitro fertilization (IVF) is also less likely to succeed. We herein provide an updated state-of-the-art regarding the molecular bases of what we could define as dysmetabolic infertility, focusing on the clinical aspects, as well as possible treatment.es_ES
Patrocinadordc.description.sponsorshipUniversita degli Studi di Roma La Sapienza within the CRUI-CARE Agreementes_ES
Type of licensedc.rightsAttribution-NonCommercial-NoDerivs 3.0 United States*
Link to Licensedc.rights.uri*
Sourcedc.sourceClinical Endocrinologyes_ES
Keywordsdc.subjectAssisted reproductive technologyes_ES
Keywordsdc.subjectBody mass indexes_ES
Keywordsdc.subjectIn vitro fertilizationes_ES
Keywordsdc.subjectPolycystic ovary syndromees_ES
Títulodc.titleFemale infertility in the era of obesity: the clash of two pandemics or inevitable consequence?es_ES
Document typedc.typeArtículo de revistaes_ES
dc.description.versiondc.description.versionVersión publicada - versión final del editores_ES
dcterms.accessRightsdcterms.accessRightsAcceso abiertoes_ES
Indexationuchile.indexArtículo de publícación WoSes_ES

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Attribution-NonCommercial-NoDerivs 3.0 United States
Except where otherwise noted, this item's license is described as Attribution-NonCommercial-NoDerivs 3.0 United States