Now showing items 36701-36720 of 98071

    • Morales, Javier O.; Fathe, Kristin R.; Brunaugh, Ashlee; Ferrati, Silvia; Li, Song; Montenegro-Nicolini, Miguel; Mousavikhamene, Zeynab; McConville, Jason T.; Prausnitz, Mark R.; Smyth, Hugh D.C. (Springer New York LLC, 2017)
      © 2017, American Association of Pharmaceutical Scientists. Biologic products are large molecules such as proteins, peptides, nucleic acids, etc., which have already produced many new drugs for clinical use in the last ...
    • Leal Fuentes, Ingrid G.; Molina, Temistocles; Montero, Adela; González, Carolina (Ediciones Mayo S.A., 2016)
      ©2016 Ediciones Mayo, S.A. All rights reserved. Objective: To assess the side effects with the use of etonogestrel subdermal contraceptive implant (ESCI) in Chilean adolescents. Patients and methods: Cohort users ESCI ...
    • Motes-Rodrigo, Alba; Labra, Antonieta; Lampe, Helene M. (Blackwell Publishing Ltd, 2017)
      © 2017 Blackwell Verlag GmbH In songbirds, the development of the species-specific adult song involves a learning process that varies in extension. In species that incorporate new song elements throughout life (open-ended ...
    • Cisternas, Ignacio Sepúlveda; Torres, Alexia; Flores, Andrés Fuentes; Angulo, Víctor Antonio García (BioMed Central Ltd., 2017)
      © 2017 The Author(s). Background: Riboflavin is the precursor of important redox cofactors such as flavin mononucleotide (FMN) and flavin adenine dinucleotide, required for several biological processes. Vibrio cholerae, a ...
    • Paredes Zúñiga, Susana; Morales, Rodrigo A.; Muñoz Sánchez, Salomé; Muñoz Montecinos, Carlos Humberto.; Parada, Margarita; Tapia, Karina; Rubilar, Carlos; Allende Connelly, Miguel; Peña, Oscar A. (Springer Verlag, 2017)
      © 2017, Springer-Verlag Berlin Heidelberg. Neutrophils are a major component of the innate immune response and the most abundant circulating cell type in humans and zebrafish. The CXCL12/CXCR4 ligand receptor pair plays a ...
    • Varas, Macarena; Fariña, Alonso; Díaz Pascual, Francisco; Ortíz-Severín, Javiera; Marcoleta, Andrés E.; Allende Connelly, Miguel; Santiviago, Carlos A.; Chávez, Francisco P. (Elsevier B.V., 2017)
      © 2017The zebrafish model has been used to determine the role of vertebrate innate immunity during bacterial infections. Here, we compare the in vivo immune response induced by GFP-tagged Salmonella Typhimurium inoculated ...
    • Del Canto, Felipe; O'Ryan Gallardo, Miguel; Pardo, Mirka; Torres, Alexia; Gutiérrez, Daniela; Cádiz, Leandro; Valdés, Raul; Mansilla, Aquiles; Martínez, Rodrigo; Hernández, Daniela; Caro, Benjamin; Levine, Myron M.; Rasko, David A.; Hill, Christopher M.; Pop, Mihai; Stine, O. Co (Frontiers Media S.A., 2017)
      © 2017 Del Canto, O'Ryan, Pardo, Torres, Gutiérrez, Cádiz, Valdés, Mansilla, Martínez, Hernández, Caro, Levine, Rasko, Hill, Pop, Stine and Vidal.Enterotoxigenic Escherichia coli (ETEC) is one of the most common causes of ...
    • Urzúa Salinas, Cristhian; Guerrero, Julia; Gatica, Hector; Velasquez, Victor; Goecke Sariego, Irmgadt (Association for Research in Vision and Ophthalmology Inc., 2017)
      © 2017 The Authors. PURPOSE. This study is aimed to investigate the role of glucocorticoid receptor (GR) isoforms in peripheral blood mononuclear cells (PBMC) as biomarkers of glucocorticoid (GC) resistance and to validate ...
    • del Campo, Miguel; Zhong, Ta- Ying; Tampe, Ricardo; García Nannig, Lorena; Lagos, Néstor (Elsevier Ltd, 2017)
      © 2016 Elsevier LtdOne of the proposed mechanisms to explain why Diarrhetic Shellfish Poison (DSP) toxins are tumor promoters is founded on the capacity of these toxins to increase TNF-α secretion. Although macrophages are ...
    • Muñoz San Martín, Catalina; Apt Baruch, Werner; Zulantay Alfaro, Inés (Elsevier B.V., 2017)
      © 2017 Elsevier B.V. The protozoan Trypanosoma cruzi is the causative agent of Chagas disease, a major public health problem in Latin America. This parasite has a complex population structure comprised by six or seven major ...
    • Montes, Matías; Moreira Ramos, Sandra; Rojas, Diego A.; Urbina, Fabiola; Käufer, Norbert F.; Maldonado, Edio (Blackwell Publishing Ltd, 2017)
      © 2017 Federation of European Biochemical Societies In Schizosaccharomyces pombe, ribosomal protein gene (RPG) promoters contain a TATA box analog, the HomolD box, which is bound by the Rrn7 protein. Despite the importance ...
    • Elani, Hawazin W.; Harper, Sam; Thomson, William Murray; Espinoza Santander, Iris; Mejia, Gloria C.; Ju, Xiangqun; Jamieson, Lisa M.; Kawachi, Ichiro; Kaufman, Jay S. (Blackwell Munksgaard, 2017)
      © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Objectives: To conduct cross-national comparison of education-based inequalities in tooth loss across Australia, Canada, Chile, New Zealand and the United ...
    • Berríos Cárcamo, Pablo; Quintanilla González, María Elena; Herrera-Marschitz Muller, Mario; Vasiliou, Vasilis; Zapata Torres, Gerald; Rivera Meza, Mario (Frontiers Media S.A., 2017)
      © 2017 Berríos-Cárcamo, Quintanilla, Herrera-Marschitz, Vasiliou, Zapata-Torres and Rivera-Meza. Background: Several studies have shown that the ethanol-derived metabolite salsolinol (SAL) can activate the mesolimbic system, ...
    • Villanueva, Andrea A.; Falcón, Paulina; Espinoza, Natalie; Solano, R. Luis; Milla, Luis A.; Hernandez-SanMiguel, Esther; Torres, Vicente A.; Sanchez-Gomez, Pilar; Palma, Verónica (Impact Journals LLC, 2017)
      Neogenin-1 (NEO1) is a transmembrane receptor involved in axonal guidance, angiogenesis, neuronal cell migration and cell death, during both embryonic development and adult homeostasis. It has been described as a dependence ...
    • Cabello, Gertrudis; Fariña, Emilio; Jeldres, Alejandro; Rimoldi, Stefano F.; Scherrer, Urs (Interciencia Association, 2017)
      It is thought that adaptive changes protect high-altitude populations against altitude-induced diseases, but information from well controlled studies is lacking. In a prospective, controlled study, we assessed the prevalence ...
    • Moya, Mario O.; Aguirre, Claudio; Mondaca, Carlos; Cea-Nettig, Ximena; Bustamante, Claudia (Interciencia Association, 2017)
      In recent years, social sciences and disciplines such as public health disclosed versions of Chilean aging as a neutral phenomenon, as a result of the modernization process of the State and health improvements in the ...
    • Prieto-Parra, Laura; Yohannessen, Karla; Brea, Cecilia; Vidal, Daniella; Ubilla, Carlos A.; Ruiz-Rudolph, Pablo (Elsevier Ltd, 2017)
      © 2017 Elsevier Ltd The objective of this study was to determine the association of respiratory symptoms and medication use and exposure to various air pollutants, PM2.5components, and source factors in a panel of asthmatic ...
    • Leiva, Loreto; George, Myriam; Antivilo, Andrés; Squicciarini, Ana María; Simonsohn, Ariela; Vargas, Belén; Guzmán, Javier (Pontificia Universidad Catolica de Valparaiso, 2015)
      Within the scope of the program "Habilidades para la Vida" (Skills for Life), we identified and evaluated children deemed as at-risk, who participated in the Program's preventive activities. We evaluated if they exhibited ...
    • Schmeda-Hirschmann, Guillermo; Gomez, Celeste Vega; Rojas de Arias, Antonieta; Burgos-Edwards, Alberto; Alfonso, Jorge; Rolon, Miriam; Brusquetti, Francisco; Netto, Flavia; Urra, Félix A.; Cárdenas, César (Elsevier Ireland Ltd, 2017)
      © 2017 Elsevier Ireland Ltd Ethnopharmacological relevance Toads belonging to genus Rhinella are used in Paraguayan traditional medicine to treat cancer and skin infections. Aim of the study The objective of the study was ...
    • Villalobos, Claudio; Maldonado Arbogast, Pedro; Valdés, José L. (Public Library of Science, 2017)
      © 2017 Villalobos et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the ...