Artículos de revistas: Recent submissions

Now showing items 541-560 of 11560

    • Epitranscriptomic regulation of HIV-1 full-length RNA packaging 
      Pereira Montecinos, Camila; Toro Ascuy, Daniela; Ananías Sáez, Catarina; Gaete Argel, Aracelly; Rojas Fuentes, Cecilia; Riquelme Barrios, Sebastián; Rojas Araya, Bárbara; García de Gracia, Francisco; Aguilera Cortés, Paulina; Chnaiderman Figueroa, Jonas; Acevedo Acevedo, Mónica; Valiente Echeverría, Fernando; Soto Rifo, Ricardo (Oxford University Press, 2022)
      During retroviral replication, the full-length RNA serves both as mRNA and genomic RNA. However, the mechanisms by which the HIV-1 Gag protein selects the two RNA molecules that will be packaged into nascent virions remain ...
    • Clinical and dermatoscopic predictors of squamous cell carcinoma of the lips: a case-control, multicentric study 
      Lallas, A.; Martínez, G.; Arceu, M.; Kyrgidis, A.; Liopyris, K.; Brancaccio, G.; Longo, C.; Errichetti, E.; Sgouros, D.; Papageorgiou, C.; Fotiadou, C.; Siskou, S.; Manoli, S. M.; Sotiriou, E.; Ioannides, D.; Katoulis, A.; Lazaridou, E.; Todorovska, V.; Argenziano, G.; Apalla, Z. (Wiley, 2022)
      Background Squamous cell carcinoma of the lip accounts for 20% of all oral carcinomas. Its diagnosis may be challenging because it clinically resembles actinic cheilitis and inflammatory lesions of the lips. Objectives To ...
    • Ethical issues of organ donation after circulatory death: considerations for a successful implementation in Chile 
      Pérez Castro, Pablo; Salas, Sofia P. (Wiley, 2021)
      Organ transplantation is a lifesaving procedure for end-organ damage and remains up to today as the most cost-effective alternative to treat these conditions. However, the main limitation to performing organ transplants ...
    • Regulation of leaderless mRNA translation in bacteria 
      Leiva, Lorenzo Eugenio; Katz Zondek, Assaf (MDPI, 2022)
      In bacteria, the translation of genetic information can begin through at least three different mechanisms: canonical or Shine-Dalgarno-led initiation, readthrough or 70S scanning initiation, or leaderless initiation. Here, ...
    • Human cDC1s display constitutive activation of the UPRsensor IRE1 
      García González, Paulina; Fernández, Dominique; Gutiérrez Cabrera, Diane; Parra Cordero, Mauro; Osorio Olivares, Fabiola (Wiley, 2022)
      The intracellular mechanisms safeguarding DC function are of biomedical interest in several immune-related diseases. Type 1 conventional DCs (cDC1s) are prominent targets of immunotherapy typified by constitutive activation ...
    • Magnitude of the contralateral efferent olivocochlear effect as a function of the frequency 
      Anza Miranda, Fernanda; Aguilar Vidal, Enzo (Elsevier, 2022)
      Background: The activation of the medial olivocochlear reflex reduces the cochlear gain, which is manifested perceptually as decreased auditory sensitivity. However, it has remained unclear whether the extent of this ...
    • Alzheimer’s disease and tau self-assembly: in the search of the missing link 
      González, Andrea; Singh, Sandeep Kumar; Churruca Muñoz, Macarena; Maccioni Baraona, Ricardo Benjamín (MDPI, 2022)
      Alzheimer's disease (AD) is a multifactorial neurodegenerative disease characterized by progressive cognitive impairment, apathy, and neuropsychiatric disorders. Two main pathological hallmarks have been described: ...
    • FilmArray® Meningoencephalitis panel in the diagnosis of central nervous system infections: stewardship and ... 
      Acuña Avila, Mirta; Benadof Fuentes, Dona; Yohannessen Vásquez, Karla; Leiva, Yennybeth; Clement Campillo, Pascale (BMC, 2022)
      Background: Central nervous system (CNS) infection has been an ongoing concern in paediatrics. The FilmArray (R) Meningoencephalitis (FAME) panel has greater sensitivity in identifying the aetiology of CNS infections. This ...
    • Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps 
      Adeyemo, Adebowale; Balaconis, Mary K.; Darnes, Deanna R.; Fatumo, Segun; Granados Moreno, Palmira; Hodonsky, Chani J.; Inouye, Michael; Kanai, Masahiro; Kato, Kazuto; Knoppers, Bartha M.; Lewis, Anna C. F.; Martin, Alicia R.; McCarthy, Mark I.; Meyer, Michelle N.; Okada, Yukinori; Richards, J. Brent; Richter, Lucas; Ripatti, Samuli; Rotimi, Charles N.; Sanderson, Saskia C.; Sturm, Amy C.; Verdugo Salgado, Ricardo Alejandro; Widen, Elisabeth; Willer, Cristen J.; Wojcik, Genevieve L.; Zhou, Alicia (Nature Research, 2021)
      Polygenic risk scores (PRSs) aggregate the many small effects of alleles across the human genome to estimate the risk of a disease or disease-related trait for an individual. The potential benefits of PRSs include ...
    • FR - Área tumoral calculada y densidad de Breslow, dos nuevos parámetros pronósticos en la evaluación ... 
      Bosch Amate, X.; Vargas Mora, Pablo Andrés; Morgado Carrasco, D. (Elsevier, 2021)
    • Polypoid melanoma: Towards a dermoscopic approach 
      Rojas Erazo, Camilo Omar; Valenzuela Ahumada, Fernando Alfredo; Carreño Toro, Laura Elisa; González Coloma, Francisco (Mattioli 1885, Italy, 2021)
    • "White dot syndromes", an inappropriate and outdated misnomer 
      Neri, Piergiorgio; Herbort, Carl P.; Hedayatfar, Alireza; Tugal Tutkun, Ilknur; Cimino, Luca; Urzúa Salinas, Cristhian Alejandro; Papasavvas, Ioannis; Takeuchi, Masuru; Lages, Vania (Springer, 2022)
    • Inicios de la especialidad y los cuidados intensivos neonatales en Chile 
      Hosiasson, Stefan; Beca, Juan Pablo; Vaisman Weinstein, Sergio (Elsevier, 2021)
      La historia de los inicios en Chile de la implementación nacional de las unidades de cuidados intensivos neonatales, y por ende de los inicios de la neonatología moderna en Chile, es de visionarios motivados exclusivamente ...
    • Allergens of the urushiol family promote mitochondrial dysfunction by inhibiting the electron transport at ... 
      Pacheco, Rodrigo; Quezada, Sergio A.; Kalergis, Alexis M.; Becker, María Inés; Ferreira, Jorge; Ioannes, Alfredo E. de (Sociedad de Biología de Chile, 2021)
      Background: Urushiols are pro-electrophilic haptens that cause severe contact dermatitis mediated by CD8+ efector T-cells and downregulated by CD4+ T-cells. However, the molecular mechanism by which urushiols stimulate innate ...
    • Dementia caregiving across Latin America and the Caribbean and brain health diplomacy 
      Ibáñez, Agustín; Pina Escudero, Stefanie Danielle; Possin, Katherine L.; Quiroz, Yakeel T.; Aguzzoli Peres, Fernando; Slachevsky Chonchol, Andrea María; Sosa, Ana Luisa; Brucki, Sonia M. D.; Miller, Bruce L (Elsevier, 2021)
      The prevalence of dementia in Latin America and the Caribbean is growing rapidly, increasing the burden placed on caregivers. Exacerbated by fragile health-care systems, unstable economies, and extensive inequalities, ...
    • Dysregulated immune responses in COVID-19 patients correlating with disease severity and invasive oxygen ... 
      García González, Paulina; Tempio Sepúlveda, Fabián Ignacio; Fuentes, Camila; Merino, Consuelo; Vargas, Leonardo; Simon, Valeska; Ramírez Pereira, Mirliana; Rojas, Verónica; Tobar Almonacid, Eduardo Andres; Landskron Ramos, Glauben Tamara; Araya, Juan Pablo; Navarrete, Mariela; Bastías Oñate, Carla Belén; Tordecilla Fernández, Rocío Pilar; Varas, Macarena A.; Maturana, Pablo; Marcoleta Caldera, Andrés Esteban; Allende Connelly, Miguel Luis; Naves Pichuante, Rodrigo Antonio; Hermoso, Marcela Alejandra; Salazar Onfray, Flavio Andrés; López Nitsche, Mercedes Natalia; Bono Merino, María Rosa; Osorio Olivares, Fabiola Beatriz (Frontiers Media, 2021)
      The prognosis of severe COVID-19 patients has motivated research communities to uncover mechanisms of SARS-CoV-2 pathogenesis also on a regional level. In this work, we aimed to understand the immunological dynamics of ...
    • Nursing interventions for patient empowerment during intensive care unit discharge: a systematic review 
      Cuzco, Cecilia; Torres Castro, Rodrigo Hernán; Torralba, Yolanda; Manzanares, Isabel; Muñoz Rey, Pilar; Romero García, Marta; Martínez Momblan, Ma. Antonia; Martínez Estalella, Gemma; Delgado Hito, Pilar; Castro, Pedro (MDPI, 2021)
      Intensive care unit discharge is an important transition that impacts a patient's wellbeing. Nurses can play an essential role in this scenario, potentiating patient empowerment. A systematic review was conducted using the ...
    • Central catheter-associated Deep vein thrombosis in cancer: clinical course, prophylaxis, treatment 
      Marín Valdés, Arnaldo Andrés; Bull, Leonardo; Kinzie, Matthew; Andresen, Max (BMJ, 2021)
      The adequate handling of central venous catheters is a key element in the management of patients with cancer. Catheter-associated deep vein thrombosis is frequently observed in patients with malignant diseases; ...
    • Cardiac rehabilitation in a patient with severe heart failure and ventricular septal defect secondary to ... 
      Mazzucco Vezzera, Guillermo Andres; Pilon, Leonardo; Escalante, Juan Pablo; Chichizola, Nicolás; Torres Castro, Rodrigo Hernán (Cureus Inc, 2021)
      The treatment of choice for patients with advanced heart failure (HF) and with limiting symptoms with evidence of a poor prognosis despite optimal conventional treatment is a heart transplant. However, there is little ...
    • Tackling ischemic reperfusion injury with the aid of stem cells and tissue engineering 
      Zamorano, Mauricio; Castillo Peñaloza, Rodrigo Luis; Beltran, Jorge F.; Herrera, Lisandra; Farías, Joaquín A.; Antileo, Christian; Aguilar Gallardo, Cristóbal; Pessoa, Adalberto; Calle, Yolanda; Farías, Jorge G. (Frontiers Media, 2021)
      Ischemia is a severe condition in which blood supply, including oxygen (O), to organs and tissues is interrupted and reduced. This is usually due to a clog or blockage in the arteries that feed the affected organ. ...