Now showing items 801-820 of 11583

    • Blanco, Rances; Carrillo Beltrán, Diego Antonio; Muñoz, Juan P.; Corvalán, Alejandro H.; Calaf, Gloria M.; Aguayo, Francisco (MDPI, 2021)
      Simple Summary Breast cancer (BC) is the most frequent tumor in women worldwide. A minority of BC patients have a family history of the disease, suggesting the importance of environmental and lifestyle factors. Human ...
    • Sánchez Ramírez, Diana C.; Normand, Kaylene; Yang, Zhaoyun; Torres Castro, Rodrigo Hernan; Torres Castro, Rodrigo Hernán (MDPI, 2021)
      Background: The long-term impact of COVID-19 is still unknown. This study aimed to explore post COVID-19 effects on patients chest computed tomography (CT), lung function, respiratory symptoms, fatigue, functional capacity, ...
    • Rozas Rojas, Pablo Sebastián; Pinto, Cristina; Martínez Traub, Francisca José; Díaz Hinojosa, Rodrigo Ignacio; Pérez, Viviana; Becerra, Daniela; Ojeda, Patricia; Ojeda, Jorge; Wright, Madison T.; Mella, Jéssica; Plate, Lars; Henríquez, Juan Pablo; Hetz Flores, Claudio Andrés; Bilches Medinas, Danilo (BMC, 2021)
      Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for ALS. Mice ...
    • Jorquera, Gonzalo; Russell, Javier; Monsalves Álvarez, Matías; Cruz, Gonzalo; Valladares-Ide, Denisse; Basualto Alarcón, Carla Edith; Barrientos, Genaro; Estrada, Manuel; Llanos, Paola (MDPI, 2021)
      Among multiple mechanisms, low-grade inflammation is critical for the development of insulin resistance as a feature of type 2 diabetes. The nucleotide-binding oligomerization domain-like receptor family (NOD-like) pyrin ...
    • Cottin Arredondo, Marianne; Hernández, Cristóbal; Núñez, Catalina; Labbé, Nicolás; Quevedo Labbé, Iván Yamil; Davanzo, Antonella; Behn, Alex (Frontiers Media, 2021)
      Distinct sources of stress have emerged during the COVID-19 pandemic. Particularly, fear is expected to generate significant psychological burden on individuals and influence on either unsafe behavior that may hinder ...
    • Olivarría, Verónica V.; Campodónico, Paola; Vollrath, Valeska; Von Geldern, Paula; Velásquez, Carolina; Pavez, Patricia; Valente, Bárbara; Donoso, Pamela; Ginesta Frings, Carmen Alexandra; Cavada, Gabriel; Mazzon, Enrico; Navia, Víctor; Guzmán, Matías; Brinck, Pablo; Lavados, Pablo M. (Lippincott Williams & Wilkins, 2021)
      Background: A poor or unhealthy diet is responsible for an important fraction of ischemic stroke risk. Adherence to dietary patterns, such as the Mediterranean diet, rich in monounsaturated fatty acids mainly from olive ...
    • Sepúlveda Rivas, Sabrina; Leal, Matías S.; Pedrozo Cibils, Zully Rocío Evangelina; Kogan, Marcelo Javier; Ocaranza Jeraldino, María Paz Alejandra; Morales Montecinos, Javier Octavio (MDPI, 2021)
      Ang-(1-9) peptide is a bioactive vasodilator peptide that prevents cardiomyocyte hypertrophy in vitro and in vivo as well as lowers blood pressure and pathological cardiovascular remodeling; however, it has a reduced ...
    • Ayala, Ana; Christensson, Kyllike; Christensson, Eva; Cavada Chacon, Gabriel Alfredo; Erlandsson, Kerstin; Velandia, Marianne (Wiley, 2021)
      Aim Separating infants and their parents after a Caesarean section is still the routine care worldwide. This study investigated three caregiving models on the wakefulness and physiological parameters of full-term infants ...
    • Rivera, Eugenio; Canales, Claudio; Pacheco, Matías; García Herrera, Claudio; Macías, Demetrio; Celentano, Diego J.; Herrera Videla, Emilio Augusto (Nature, 2021)
      The present study involves experiments and modelling aimed at characterizing the passive structural mechanical behavior of the chronic hypoxic lamb thoracic aorta, whose gestation, birth and postnatal period were carried ...
    • Thompson, Luis; Porte, Lorena; Díaz, Violeta; Díaz Jarabran, María Cristina; Solar, Sebastián; Valenzuela, Pablo; Norley, Nicole; Pires, Yumai; Carreño, Fernando; Valenzuela, Sergio; Shabani, Rukmane; Rickerts, Volker; Weitzel, Thomas Fritz (MDPI, 2021)
      We describe a case of chronic meningoencephalitis with hydrocephalus caused by Cryptococcus bacillisporus (VGIII) in an immunocompetent patient from Santa Cruz, Bolivia. This first report of a member of the Cryptococcus ...
    • Chuang Chuang, Angela; Ramos Hernández, Hernán; Zelada Bacigalupo, Ursula Andrea; López Castillo, María Teresa; Villavicencio Landeros, Leonel; Montecinos Peret, Luisa; González Muñoz, Claudio Andrés; Barría Espinoza, Tamara Alejandra; Izquierdo Copiz, Giannina (Sociedad Chilena de Infectología, 2021)
      Introducción: La infección congénita por citomegalovirus (CMVc) es la causa más frecuente de infección intrauterina, 90% de los recién nacidos (RN) son asintomáticos al nacer y 6 a 15% desarrollarán secuelas a largo ...
    • Burgos Concha, Pablo Ignacio; Cruz, Gabriela; Hawkes, Teresa; Rojas Sepúlveda, Ignacia; Woollacott, Marjorie (Frontiers Media, 2021)
      Physical and mental training are associated with positive effects on executive functions throughout the lifespan. However, evidence of the benefits of combined physical and mental regimes over a sedentary lifestyle remain ...
    • Gómez Virgilio, Laura; Luarte Navarro, Alejandro Ernesto; Ponce de la Vega, Daniela Paz; Bruna Jara, Bárbara Alexandra; Behrens Pellegrino, María Isabel Ofelia (MDPI, 2021)
      Among all the proposed pathogenic mechanisms to understand the etiology of Alzheimer's disease (AD), increased oxidative stress seems to be a robust and early disease feature where many of those hypotheses converge. However, ...
    • Sotomayor Campos, Camilo Germán; Mendoza, Marcelo; Castañeda Zeman, Víctor Antonio; Farías, Humberto; Molina, Gabriel; Pereira Retamales, Gonzalo Leopoldo; Hartel, Steffen; Solar, Mauricio; Araya, Mauricio (MDPI, 2021)
      Medical imaging is essential nowadays throughout medical education, research, and care. Accordingly, international efforts have been made to set large-scale image repositories for these purposes. Yet, to date, browsing of ...
    • Renner, Alex; Burotto, Mauricio; Valdés, José Miguel; Román Sobarzo, Juan Carlos; Walton Díaz, Annerleim Nylsello (SAGE, 2021)
      Immunotherapy, in the form of immune checkpoint inhibitors (ICI), has shown activity in metastatic urothelial bladder carcinoma, resulting in the approval of several ICI agents in the first- and second-line settings. ...
    • Arancibia, Trinidad; Morales Pisón, Sebastián; Maldonado Maldonado, Edio Luis; Jara Sosa, Lilian Elena (Sociedad de Biología de Chile, 2021)
      Breast cancer (BC), a heterogeneous, aggressive illness with high mortality, is essentially a genomic disease. While the high-penetrance genes BRCA1 and BRCA2 play important roles in tumorigenesis, moderate- and ...
    • Le Roy, Catalina; Barja, S.; Sepúlveda, C.; Guzmán, M. L.; Olivarez, M.; Figueroa, M. J.; Álvarez, M. (Elsevier España, 2021)
      Introducción: Los niños y adolescentes con parálisis cerebral (PC) tienen mayor riesgo de desnutrición y deficiencias de micronutrientes. Dos de los que podemos estudiar y tratar son la vitamina D (VD) y el hierro. No ...
    • Núñez Cortés, Rodrigo Ignacio; Rivera Lillo, Gonzalo Bernardo; Arias Campoverde, Marisol; Soto García, Darío; García Palomera, Roberto; Torres Castro, Rodrigo Hernán (SAGE, 2021)
      We propose the use of the 1-minute sit-to-stand test (1STST) to evaluate the physical capacity and exertional desaturation one month after discharge in a sample of patients who survived COVID-19 pneumonia. This was ...
    • Cannoni Berd, Gigliola Carolina; Ribbeck Baraibar, Daniela Andrea; Hernández, Olivia; Casacuberta Volpato, María Jesús (Elsevier, 2021)
      La infección por Chlamydia trachomatis es la infección de transmisión sexual bacteriana más frecuente en el mundo. En este artículo se revisa la prevalencia reportada en Chile, cuadro clínico, diagnóstico, tratamiento, ...
    • Riquelme, Denise; Cerda Arancibia, Oscar Alejandro; Leiva Salcedo, Elías (Frontiers Media, 2021)
      TRPM4 is a non-selective cation channel activated by intracellular calcium and permeable to monovalent cations. This channel participates in the control of neuronal firing, neuronal plasticity, and neuronal death. TRPM4 ...