Now showing items 821-840 of 11583

    • Aguilera, Bernardo (Sociedad Médica de Santiago, Chile, 2021)
      Background: An increasingly large proportion of clinical trials is being conducted at non-traditional geographic regions such as Latin America. However, concerns have been raised that hosting countries may lack adequate ...
    • Carrasco, Cristian; Tittarelli, Andrés; Paillaleve, Natalia; Pozo, Maeva del; Rojas Sepúlveda, Daniel Alberto; Barría Catricura, Omar André; Fluxá Rojas, Paula Andrea; Hott, Melissa; Martin, Carolina; Quezada Monrás, Claudia Andrea; Salazar Onfray, Flavio Andres (MDPI, 2021)
      Gallbladder cancer (GBC) is an aggressive and highly lethal disease with relatively low global incidence, but one that constitutes a major health problem in Asian and Latin American countries, particularly in Chile. The ...
    • Sepúlveda, Daniela A.; Barrueto, Gonzalo; Correa, Margarita C. G.; Castañeda Sepúlveda, Luis Eduardo; Figueroa, Christian C. (MDPI, 2021)
      Global warming will increase pest insect population sizes and diminish the effectiveness of biological control. This biological control failure scenario appears to be of particular concern for areas with a significant ...
    • Brenet Rivas, Marianne del Pilar; Martínez, Samuel; Pérez Núñez, Ramón; Pérez González, Leonardo Andrés; Contreras, Pamela; Díaz, Jorge; Ávalos, Ana María; Schneider, Pascal; Quest, Andrew Frederick Geoffery; Leyton Campos, Lisette (Frontiers Media, 2021)
      Cancer cell adhesion to the vascular endothelium is an important step in tumor metastasis. Thy-1 (CD90), a cell adhesion molecule expressed in activated endothelial cells, has been implicated in melanoma metastasis by ...
    • Martínez, Nicolás W.; Gómez, Felipe E.; Matus, Soledad (Frontiers Media, 2021)
      There is a growing evidence describing a decline in adaptive homeostasis in agingrelated diseases affecting the central nervous system (CNS), many of which are characterized by the appearance of non-native protein ...
    • Zamora, Tomás; Sandoval, Felipe; Demandes, Hugo; Serrano, Javier; González, Javiera; Lira, María Jesús; Klaber, Ianiv; Carmona, Maximiliano; Botello, Eduardo; Schweitzer, Daniel (Sage, 2021)
      Introduction: Hip fracture patients have been severely affected by the COVID-19 pandemic; however, the sub acute effects of a concomitant SARS-CoV-2 infection and the outcomes in highly exposed developing countries are ...
    • Brañes, Julián; Barahona Vásquez, Maximiliano; Carvajal, Sebastián; Wulf Ibáñez, Rodrigo; Barrientos Mendoza, Cristián (BMC, 2021)
      Purpose Currently, patient-reported outcome measures (PROMs) are the standard instruments used to compare arthroplasty results. Goodman et al. recently published a well-constructed scale with excellent psychometric properties ...
    • Moraga, Fernando A.; Reyes Catalán, Roberto; Ebensperger Darrouy, Germán; López, Vasthi; Llanos Mansilla, Jorge Aníbal (Frontiers Media, 2021)
      The authors previously demonstrated that newborn llama (NBLL) express high levels of α1 adrenergic receptors, which provide a potent vasoconstriction response when compared with newborn sheep (NBSH) gestated at sea level. ...
    • Navarro, Francisco; Leiva, Lissette; Norero, Enrique (Oxford, 2021)
      Pancreatic pseudocyst is a common complication of acute and chronic pancreatitis. However, spleen involvement in pancreatitis is rare. We present a patient with a pancreatic tail pseudocyst with splenic extension and ...
    • Rivera Lillo, Gonzalo Bernardo; Stamatakis, Emmanuel; Bekinschtein, Tristan A.; Menon, David K.; Chennu, Srivas (Nature, 2021)
      The overt or covert ability to follow commands in patients with disorders of consciousness is considered a sign of awareness and has recently been defined as cortically mediated behaviour. Despite its clinical relevance, ...
    • Maldonado Maldonado, Edio Luis; Morales Pisón, Sebastián; Urbina, Fabiola; Solari Illescas, Aldo Gerónimo (Frontiers Media, 2021)
      Trypanosomatids are a group of primitive unicellular eukaryotes that can cause diseases in plants, insects, animals, and humans. Kinetoplast genome integrity is key to trypanosomatid cell survival and viability. Kinetoplast ...
    • Torres Castro, Rodrigo Hernán; Vasconcello Castillo, Luis Eduardo; Puppo Gallardo, Homero Luis; Cabrera Aguilera, Ignacio; Otto Yáñez, Matías; Rosales Fuentes, Javiera Paz; Vilaro, Jordi (MDPI, 2021)
      Obstructive sleep apnoea (OSA) constitutes a public health problem, with various systemic consequences that can increase cardiovascular morbidity and mortality as well as increase healthcare expenditure. This review discusses ...
    • Cuesta Astroz, Yesid; Gischkow Rucatti, Guilherme; Murgas, Leandro; San Martín Rovirosa, Carol; Sanhueza, Mario; Martin, Alberto J. M. (Frontiers Media, 2021)
      Gene Regulatory Networks (GRNs) allow the study of regulation of gene expression of whole genomes. Among the most relevant advantages of using networks to depict this key process, there is the visual representation of large ...
    • Gutiérrez Contreras, Esteban; Glavic Maurer, Álvaro Alberto; Brand, Andrea; Sierralta Jara, Jimena Alejandra (Soc. Neuroscience, 2021)
      The adaptable transcriptional response to changes in food availability not only ensures animal survival but also lets embryonic development progress. Interestingly, the CNS is preferentially protected from periods of ...
    • White, Sarah J.; Gerber Pluss, Denise Verónica; Sánchez Hernández, Romina D.; Efiannay, Anthonia; Chowdhury, Ishita; Partington, Hannah; Moss, Joanna F. (Cambridge University Press, 2021)
      Background Research on women with the fragile-X premutation (FX-p) has been underrepresented within the field of behavioural phenotypes. Aims To understand whether the FX-p confers risk for autistic traits, depression ...
    • Besomi, Javier; Escobar Bravo, Valeria Soledad; Álvarez, Santiago; Valderrama, Juanjose; López, Jaime; Mella, Claudio; Lara, Joaquín; Meneses Alvarado, Claudio Eugenio (British Editorial Society of Bone & Joint Surgery, England, 2021)
      Purpose This study investigated the association between chondrolabral damage and time to arthroscopic surgery for slipped capital femoral epiphysis (SCFE). Methods This was a descriptive retrospective study that enrolled ...
    • Bezmalinovic Colleoni, Alejandro Slavo; Rivera, Eugenio; García Herrera, Claudio Moisés; Celentano, Diego Javier; González Candia, Alejandro Antonio; Herrera, Emilio A. (Univ Fed Rio de Janeiro, Brazil, 2021)
      Para evaluar de manera fidedigna el riesgo de ruptura de la aorta – junto a los índices de peligrosidad de enfermedades cardiovasculares u otras condiciones extremas y los efectos de posibles tratamientos – se requiere conocer ...
    • Ladrón de Guevara, David H.; Bitar Hirmas, Patricia; Soto S., Juan Ramón (Soc Chilena Infectología, 2021)
      La endocarditis infecciosa (EI) es una enfermedad de alta mortalidad, caracterizada por una infección endocárdica y frecuentes complicaciones multiorgánicas, que requiere un diagnóstico rápido y preciso, y un manejo ...
    • Niño Taravilla, Carmen; Otaola Arca, Hugo; Lara Aguilera, Natalie Andrea; Zuleta Morales, Yuri Iván; Ortiz Fritz, Paula Lorena (Centers Disease Control & Prevention, USA, 2021)
      We describe 26 children with multisystem inflammatory syndrome associated coronavirus disease in the pediatric intensive care unit of Roberto del Rio Hospital (Santiago, Chile). In total, 10 (38.5%) children required ...
    • San Martín, Evelyn; Carvajal Villarroel, Felipe; Cifuentes, Alexander; Dalmazzo, Dandaro; Alarcón, Freddy; Fariña, Ariel; Yáñez, Loreto (Cureus, 2021)
      Glioblastoma (GB) is the most frequent and aggressive primary tumor of the central nervous system (CNS) in adults. Standard treatment is complete tumor resection followed by concomitant radiochemotherapy (RCT) and subsequent ...