Browsing by Author "c86e411b-74d4-436b-9f9e-2f632fd22a86"
Now showing items 1-20 of 35
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Contreras, Gustavo F.; Castillo, Karen; Enrique, Nicolás; Carrasquel Ursulaez, Willy; Castillo, Juan Pablo; Milesi, Verónica; Neely, Alan; Alvarez, Osvaldo; Ferreira, Gonzalo; Gonzalez, Carlos; Latorre, Ramón (Taylor and Francis Inc., 2013)Calcium and voltage-activated potassium (BK) channels are key actors in cell physiology, both in neuronal and non-neuronal cells and tissues. Through negative feedback between intracellular Ca2+ and membrane voltage, BK ...
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Cecchi, Ximena; Alvarez, Osvaldo; Latorre, Ramón (1981)Keyhole limpet hemocyanin forms ion-conducting channels in planar lipid bilayer membranes. Ionic current through the open hemocyanin channel presents the following characteristics: (a) it is carried mainly by cations; (b) ...
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Venegas Yazigi, Diego; Mirza, Hameed; Lever, A. B.P.; Lough, Alan J.; Costamagna, Juan; Latorre, Ramón (International Union of Crystallography, 2000)© 2000 International Union of Crystallography.The Ru atom in the title compound, [RuCl(CH3CN)-{P(C6H5)3}2{C6H4(NH)2}]PF6·0.25H2O, has a six-coordinate octahedral geometry, with a trans arrangement of the triphenylphosphine ...
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Oberhauser, Andres; Alvarez, Osvaldo; Latorre, Ramón (1988)Several divalent cations were studied as agonists of a Ca2+-activated K+ channel obtained from rat muscle membranes and incorporated into planar lipid bilayers. The effect of these agonists on single-channel currents was ...
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Sariban-Sohraby, S.; Latorre, Ramón; Burg, Maurice; Olans, Lori; Benos, Dale (1984)High resistance epithelia actively transport sodium from the luminal side to the blood. Aldosterone and vasopressin stimulate this sodium transport system; the diuretic drug amiloride inhibits it in a reversible fashion. ...
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Behrens Pellegrino, María Isabel; Oberhauser, Andres; Bezanilla, Francisco; Latorre, Ramón (1989)Squid optic nerve sodium channels were characterized in planar bilayers in the presence of batrachotoxin (BTX). The channel exhibits a conductance of 20 pS in symmetrical 200 mM NaCI and behaves as a sodium electrode. The ...
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Venegas Yazigi, Diego; Mirza, Hameed; Lever, A. B.P.; Lough, Alan J.; Costamagna, Juan; Latorre, Ramón (International Union of Crystallography, 2000)© 2000 International Union of Crystallography.The title complex, [Ru(C2H3N)2(C6H6N2)(C18H15P)2](PF6)2.-CH4O, is the third of a series of ruthenium complexes containing two triphenylphosphine groups in a trans arrangement, ...
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Vergara Montecinos, Cecilia; Latorre, Ramón; Marrion, Neil V.; Adelman, John P. (Elsevier Ltd, 1998)Calcium-activated potassium channels are fundamental regulators of neuronal excitability, participating in interspike interval and spike-frequency adaptation. For large-conductance calcium-activated potassium (BK) channels, ...
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Miller, Christopher; Moczydlowski, Edward; Latorre, Ramón; Phillips, Marcia (1985)The recent development of techniques for recording currents through single ionic channels1 has led to the identification of a K +-specific channel that is activated by cytoplasmic Ca2+ (refs 2-12). The channel has complex ...
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Brauchi, Sebastián; Orio, Patricio; Latorre, Ramón (2004)The cold and menthol receptor, TRPM8, also designated CMR1, is a member of the transient receptor potential (TRP) family of excitatory ion channels. TRPM8 is a channel activated by cold temperatures, voltage, and menthol. ...
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Álvarez Araya, Osvaldo; González, Carlos; Latorre, Ramón (American Physiological Society, 2002)Ion channels open and close in a stochastic fashion, following the laws of probability. However, distinct from tossing a coin or a die, the probability of finding the channel closed or open is not a fixed number but can ...
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Miller, Christopher; Latorre, Ramón; Reisin, Ignacio (1987)Voltage-dependent Ca++-activated K+ channels from rat skeletal muscle were reconstituted into planar lipid bilayers, and the kinetics of block of single channels by Ba++ were studied. The Ba++ association rate varies ...
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Mathur, Chhavi; Johnson, Kory R.; Tong, Brian A.; Miranda, Pablo; Srikumar, Deepa; Basilio, Daniel; Latorre, Ramón; Bezanilla, Francisco; Holmgren, Miguel (Nature Publishing Group, 2018)© 2018 The Author(s). Local translation of membrane proteins in neuronal subcellular domains like soma, dendrites and axon termini is well-documented. In this study, we isolated the electrical signaling unit of an axon by ...
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Carrasquel Ursulaez, Willy; Álvarez Araya, Osvaldo; Bezanilla, Francisco; Latorre, Ramón (ResearchGate, 2018)
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Castillo, Juan P.; De Giorgis, Daniela; Basilio, Daniel; Gadsby, David C.; Rosenthal, Joshua J.C.; Latorre, Ramón; Holmgren, Miguel; Bezanill, Francisco (2011)The Na +/K + pump is a nearly ubiquitous membrane protein in animal cells that uses the free energy of ATP hydrolysis to alternatively export 3Na + from the cell and import 2K + per cycle. This exchange of ions produces a ...
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Carmona, Emerson M.; Peter Larsson, H.; Neely, Alan; Alvarez, Osvaldo; Latorre, Ramón; Gonzalez, Carlos (National Academy of Sciences, 2018)© 2018 National Academy of Sciences. All Rights Reserved. The voltage-gated proton (Hv1) channel, a voltage sensor and a conductive pore contained in one structural module, plays important roles in many physiological ...
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Moczydlowski, Edward; Latorre, Ramón (1983)The gating kinetics of a Ca2+-activated K+ channel from adult rat muscle plasma membrane are studied in artificial planar bilayers. Analysis of single-channel fluctuations distinguishes two Ca2+- and voltage-dependent ...
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Correa, Ana M.; Latorre, Ramón; Bezanilla, Francisco (1991)Na+ permeation through normal and batrachotoxin (BTX)-modified squid axon Na+ channels was characterized. Unmodified and toxin-modified Na+ channels were studied simultaneously in outside-out membrane patches using the ...
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Vergara Montecinos, Cecilia; Latorre, Ramón (1983)The interaction of Ca2+ and Ba2+ with a Ca2+-activated K+ channel from rabbit skeletal muscle membranes is studied in planar lipid bilayers. At [Ca2+]≥100 µM in the cis side (the side to which the vesicles are added) and ...
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Vergara Montecinos, Cecilia; Álvarez Araya, Osvaldo; Latorre, Ramón (The Rockefeller University, 1999)Using Ba2 1 as a probe, we performed a detailed characterization of an external K 1 binding site located in the pore of a large conductance Ca2 1-activated K 1 (BKCa) channel from skeletal muscle incorporated into planar ...