Now showing items 1-8 of 8

    • alpha (V) beta (3) Integrin regulates astrocyte reactivity 

      Lagos Cabre, Raúl; Álvarez, Álvaro; Kong, Milene; Burgos Bravo, Francesca; Cárdenas, Areli; Rojas Mancilla, Edgardo; Pérez Núñez, Ramón; Herrera Molina, Rodrigo; Rojas, Fabiola; Schneider, Pascal; Herrera-Marschitz Muller, Mario; Quest, Andrew F. G.; van Zundert, Brigitte; Leyton Campos, Lisette (BIOMED Central Ltd., 2017)
      Background: Neuroinflammation involves cytokine release, astrocyte reactivity and migration. Neuronal Thy-1 promotes DITNC1 astrocyte migration by engaging alpha(V)beta(3) Integrin and Syndecan-4. Primary astrocytes express ...
    • alpha(V)beta(3) Integrin regulates astrocyte reactivity 

      Lagos Cabre, Raúl; Álvarez Martínez, Alvaro; Kong Rojas, Milene; Burgos Bravo, Francesca; Cárdenas Oyarzo, Areli; Rojas Mancilla, Edgardo; Pérez Núñez, Ramón; Herrera Molina, Rodrigo; Rojas, Fabiola; Schneider, Pascal; Herrera Marschitz, Mario; Quest, Andrew F. G.; van Zundert, Brigitte; Leyton Campos, Lisette (BMC, 2017)
      Background: Neuroinflammation involves cytokine release, astrocyte reactivity and migration. Neuronal Thy-1 promotes DITNC1 astrocyte migration by engaging alpha(V)beta(3) Integrin and Syndecan-4. Primary astrocytes express ...
    • Astrocyte-to-neuron communication through integrin-engaged Thy-1/CBP/Csk/Src complex triggers neurite retraction via the RhoA/ROCK pathway 

      Maldonado, H.; Calderon, C.; Burgos Bravo, Francesca; Kobler, Oliver; Zuschratter, W.; Ramirez, O.; Härtel, S.; Schneider, P.; Quest, Andrew F. G.; Herrera-Molina, R.; Leyton, L. (Elsevier B.V., 2017)
      © 2016 Elsevier B.V. Two key proteins for cellular communication between astrocytes and neurons are αvβ3 integrin and the receptor Thy-1. Binding of these molecules in the same (cis) or on adjacent (trans) cellular membranes ...
    • Efectos pro-oxidantes del complejo Cu(I)-[GSH]2 en su interacción con hierro 

      Burgos Bravo, Francesca (Universidad de ChileCyberDocs, 2009)
    • Generation of superoxide radicals by copper-glutathione complexes: Redox-consequences associated with their interaction with reduced glutathione 

      Speisky Cosoy, Hernán; Gómez, Maritza; Burgos Bravo, Francesca; López Alarcón, Camilo Ignacio; Jullian Matthaei, Carolina; Olea Azar, Claudio; Aliaga, Margarita E. (PERGAMON-ELSEVIER SCIENCE LTD, 2009-03-01)
      The interaction between Cu2+ ions and GSH molecules leads to the swift formation of the physiologically occurring Cu(I)-[GSH](2) complex. Recently, we reported that this complex is able to reduce molecular oxygen into ...
    • Integrin-mediated transactivation of P2X7R via hemichannel-dependent ATP release stimulates astrocyte migration 

      Álvarez, Álvaro; Lagos Cabré, Raúl; Kong, Milene; Cárdenas, Areli; Burgos Bravo, Francesca; Schneider, Pascal; Quest, Andrew F. G.; Leyton Campos, Lisette (Elsevier, 2016)
      Our previous reports indicate that ligand-induced alpha(v)beta(3) integrin and Syndecan-4 engagement increases focal adhesion formation and migration of astrocytes. Additionally, ligated integrins trigger ATP release through ...
    • Single-molecule measurements of the effect of force on Thy-1/αvβ3-integrin interaction using nonpurified proteins 

      Burgos Bravo, Francesca; Figueroa, Nataniel L.; Casanova Morales, Nathalie; Quest, Andrew F. G.; Wilson, Christian A. M.; Leyton Campos, Lisette (Amer Soc Cell Biology, 2018)
      Thy-1 and alpha v beta 3 integrin mediate bidirectional cell-to-cell communication between neurons and astrocytes. Thy-1/alpha v beta 3 interactions stimulate astrocyte migration and the retraction of neuronal prolongations, ...
    • Single-molecule measurements of the effect of force on Thy-1/αvβ3-integrin interaction using nonpurified proteins 

      Burgos Bravo, Francesca; Figueroa, Nataniel L.; Casanova Morales, Nathalie; Quest, Andrew F. G.; Wilson, Christian A.M.; Leyton Campos, Lisette (American Society for Cell Biology, 2018)
      Thy-1 and αvβ3 integrin mediate bidirectional cell-to-cell communication between neurons and astrocytes. Thy-1/αvβ3 interactions stimulate astrocyte migration and the retraction of neuronal prolongations, both processes ...