Browsing by Subject "Gingival crevicular fluid"

Now showing items 1-19 of 19

    • Active MMP-8 quantitative test as an adjunctive tool for early diagnosis of periodontitis 
      Hernández Ríos, Marcela; Baeza Paredes, Mauricio Enrique; Raisanen, Ismo; Contreras Balbontín, Johanna; Tervahartiala, Taina; Chaparro, Alejandra; Sorsa, Timo; Hernández Ríos, Patricia (MDPI, 2021)
      Periodontitis is a host-mediated bacterial disease that affects the tooth attachment apparatus. Metalloproteinase-8 (MMP-8), a validated biomarker, could aid in clinical diagnosis. This study aimed to evaluate the diagnostic ...
    • Adjunctive effects of a sub-antimicrobial dose of doxycycline on clinical parameters and potential biomarkers ... 
      Emingil, Gülnur; Gürkan, Ali; Tervahartiala, Taina; Hernández, Marcela; Özgül, Semiha; Sorsa, Timo; Alassiri, Saeed (MDPI Multidisciplinary Digital Publishing Institute, 2019)
      Objectives: The aim of the present randomized, double-blind, placebo-controlled, parallel-arm study was to examine the effectiveness of a sub-antimicrobial dose of doxycycline (SDD) in combination with nonsurgical periodontal ...
    • Assessment of cardiovascular risk in women with periodontal diseases according to c-reactive protein levels 
      Da Venezia, Claudia; Hussein Rojas, Nayib Ignacio; Hernández Ríos, Marcela; Contreras Balbontín, Johanna; Morales Chvets, Alicia Alvarovna; Valdés, Macarena; Rojas, Francisca; Matamala López, Loreto; Hernández Ríos, Patricia (MDPI, 2021)
      Cardiovascular diseases (CVD) are highly prevalent non-communicable diseases worldwide. Periodontitis may act as a non-traditional cardiovascular risk (CVR) factor, linked by a low-grade systemic inflammation mediated by ...
    • Associations Between Matrix Metalloproteinase-8 and -14 and Myeloperoxidase in Gingival Crevicular Fluid ... 
      Hernández Ríos, Emma; Gamonal Aravena, Jorge Antonio; Tervahartiala, Taina; Mäntylä, Päivi; Rivera Escobar, Oriana; Dezerega Piwonka, Andrea; Dutzan, N.; Sorsa, T. (American Academy of Periodontology, 2010-11)
      Background: Matrix metalloproteinase (MMP)-8 is a central mediator in chronic periodontitis. MMP-8 can be activated by the cooperative action of otherMMPs such asMMP-14, reactive oxygen species, andmicrobial proteases. ...
    • Associations between matrix metalloproteinase-8 and-14 and myeloperoxidase in gingival crevicular fluid ... 
      Hernandez, M.; Gamonal Aravena, Jorge; Tervahartiala, T.; Mantyla, P.; Rivera, O.; Dezerega, A.; Dutzan, N.; Sorsa, T. (2010)
      Backround: Matrix metalloproteinase (MMP)-8 is a central mediator in chronic periodontitis. MMP-8 can be activated by the cooperative action of other MMPs such as MMP-14, reactive oxygen species, and microbial proteases. ...
    • Biomarkers in gingival crevicular fluid: Review of literature 
      Quesada, Jorge; Rivera Alvarez, Sonia (Universidad Costa Rica, Facultad odontología, 2017)
      Biomarkers are molecules that can be objectively measured and evaluated as indicators of normal biological processes, pathological processes or pharmacological responses to therapeutic intervention. In the crevicular ...
    • Biomarkers in oral fluids as diagnostic tool for psoriasis 
      Jiménez, Constanza; Bordagaray San Martín, María José; Villarroel, José Luis; Flores, Tania; Benadof, Dafna; Fernández, Alejandra; Valenzuela Ahumada, Fernando (MDPI, 2022)
      Psoriasis is a prevalent worldwide chronic immuno-inflammatory skin disease with various variants and atypical cases. The use of biomarkers for the diagnosis of psoriasis can favor timely treatment and thus improve the ...
    • Diagnostic accuracy for apical and chronic periodontitis biomarkers in gingival crevicular fluid: an ... 
      Baeza Paredes, Mauricio; Garrido Flores, Carlos; Hernández Ríos, Patricia; Dezerega Piwonka, Andrea; García Sesnich, Jocelyn; Strauss Avendaño, Franz; Aitken Saavedra, Juan; Lesaffre, Emmanuel; Vanbelle, Sophie; Gamonal Aravena, Jorge Antonio; Brignardello Petersen, Romina; Tervahartiala, Taina; Sorsa, Timo; Hernández Ríos, Marcela (Wiley, 2016)
      AimThe aim of this study was to assess the levels and diagnostic accuracy of a set of potential biomarkers of periodontal tissue metabolism in gingival crevicular fluid (GCF) from patients with chronic periodontitis (CP) ...
    • Early pregnancy levels of gingival crevicular fluid matrix metalloproteinases-8 and −9 are associated with ... 
      Chaparro, Alejandra; Realini, Ornella; Hernández Ríos, Marcela; Albers, Daniela; Weber, Laura; Ramírez, Valeria; Param, Fernanda; Kusanovic, Juan Pedro; Sorsa, Timo; Rice, Gregory Edward; Illanes, Sebastián E. (Wiley, 2020)
      Background Gestational diabetes mellitus (GDM) is increasing worldwide and women with a history of GDM are at risk of developing type 2 diabetes which is a risk factor for periodontitis. Aim To explore the association ...
    • Gingival crevicular fluid zinc- and aspartyl-binding protease profile of individuals with moderate/severe ... 
      Valenzuela Ahumada, Fernando; Fernández, Javier; Aroca, Marcela; Jiménez, Constanza; Albers, Daniela; Hernández Ríos, Marcela; Fernández, Alejandra (MDPI, 2020)
      Atopic dermatitis (AD) is a protease-modulated chronic disorder with heterogenous clinical manifestations which may lead to an imprecise diagnosis. To date, there are no diagnostic protease tests for AD. We explored the ...
    • Identification of IL-18 and soluble cell adhesion molecules in the gingival crevicular fluid as novel ... 
      Valenzuela, Fernando; Fernández, Javier; Jiménez, Constanza; Cavagnola, Daniela; Mancilla, Juan Felipe; Astorga, Jessica; Hernández Ríos, Emma; Fernández, Alejandra (MDPI, 2021)
      : Psoriasis is a chronic immunoinflammatory skin disease. Although its diagnosis is clinical, differences in the appearance and severity of lesions pose a challenge for clinicians worldwide. The use of accessible biomarkers ...
    • Levels of interleukin-1β, -8, and -10 and RANTES in gingnival crevicular fluid and cell populations in adult ... 
      Gamonal Aravena, Jorge Antonio; Acevedo, A.; Bascones, A.; Jorge, O.; Silva, A. (American Academy of Periodontology, 2000)
      Background: Various cytokines have been identified at sites of chronic inflammation such as periodontitis. Cytokines are synthesized in response to bacteria and their products, inducing and maintaining an inflammatory ...
    • Longitudinal analysis of metalloproteinases, tissue inhibitors of metalloproteinases and clinical parameters ... 
      Pozo, P.; Valenzuela, M.; Melej, C.; Zaldívar, M.; Puente, J.; Martínez, B.; Gamonal Aravena, Jorge Antonio (2005)
      Background: The aim of this work was to improve the assessment of the periodontal disease status through measurements of extracellular matrix metalloproteinases (MMPs) and their tissular inhibitors (TIMPs) in the ...
    • Matrix metalloproteinases and myeloperoxidase in gingival crevicular fluid provide site-specific diagnostic ... 
      Leppilahti, Jussi; Hernández Ríos, Patricia; Gamonal Aravena, Jorge Antonio; Tervahartiala, Taina; Brignardello Petersen, Romina; Mantyla, Paivi; Sorsa, Timo; Hernández, Marcela (2014)
      Aim: To identify the diagnostic accuracy of gingival crevicular fluid (GCF) candidate biomarkers to discriminate periodontitis from the inflamed and healthy sites, and to compare the performance of two independent matrix ...
    • MMP-8, TRAP-5, and OPG levels in GCF diagnostic potential to discriminate between healthy patients’, mild ... 
      Hernández, Marcela; Baeza Paredes, Mauricio; Contreras Balbontín, Johanna; Sorsa, Timo; Tervahartiala, Taina; Valdés Salgado, Macarena; Chaparro, Alejandra; Hernández Ríos, Patricia (MDPI, 2020)
      Biomarkers represent promising aids in periodontitis, host-mediate diseases of the tooth-supporting tissues. We assessed the diagnostic potential of matrix metalloproteinase-8 (MMP-8), tartrate-resistant acid phosphatase-5 ...
    • MMP-9 levels in the gingival crevicular fluid of chilean rosacea patients 
      Fernández, Javier; Jiménez, Constanza; Benadof, Dafna; Morales, Paulina; Astorga, Jéssica; Cáceres, Felipe; Hernández Ríos, Emma Marcela; Fernández, Alejandra; Valenzuela, Fernando (MDPI, 2022)
      Rosacea is a chronic inflammatory skin disease whose prevalence rates remain unknown in Chile. Laboratory benchmark testing for this disease is not useful, therefore, we aimed to evaluate the gingival crevicular fluid (GCF) ...
    • Niveles de piridinolina (ICTP) en el fluido gingival crevicular (FGC) en la periodontitis crónica 
      González Quesada, Jorge; Rivera Álvarez, Sonia (Universidad de Costa Rica, Facultad de Odontología, 2016)
      Pyridinoline (ICTP) is a molecule of collagen degradation that after bone resorption and degradation of the collagen matrix is released into the circulation and can not pass anabolic pathways and reused during collagen ...
    • Periodontitis and placental growth factor in oral fluids are early pregnancy predictors of gestational ... 
      Chaparro, Alejandra; Zúñiga, Edgardo; Varas-Godoy, Manuel; Albers, Daniela; Ramírez, Valeria; Hernández, Marcela; Kusanovic, Juan Pedro; Acuña-Gallardo, Stephanie; Rice, Gregory; Illanes, Sebastián E. (Wiley-Blackwell, 2018)
      © 2018 American Academy of Periodontology. Background: Gestational diabetes mellitus (GDM) affects around 7% to 10% of all pregnancies. Early detection of predisposition to GDM is the first step in developing efficacious ...
    • Pro-oxidant status and matrix metalloproteinases in apical lesions and gingival crevicular fluid as potential ... 
      Dezerega, Andrea; Madrid, Sonia; Mundi, Veránica; Valenzuela, María; Garrido, Mauricio; Paredes, Rodolfo; García Sesnich, Jocelyn; Ortega, Ana; Gamonal Aravena, Jorge Antonio; Hernández, Marcela (2012)
      Background: Oxidative stress and matrix metalloproteinases -9 and -2 are involved in periodontal breakdown, whereas gingival crevicular fluid has been reported to reflect apical status. The aim of this study was ...