Now showing items 1-5 of 5

    • Peña Oyarzún, Daniel; Troncoso Cotal, Rodrigo; Kretschmar, Catalina; Hernando, Cecilia; Budini, Mauricio; Morselli, Eugenia; Lavandero González, Sergio; Criollo Céspedes, Alfredo (Impact Journals, 2017)
      Various intracellular mechanisms are activated in response to stress, leading to adaptation or death. Autophagy, an intracellular process that promotes lysosomal degradation of proteins, is an adaptive response to several ...
    • Criollo Céspedes, Alfredo; Senovilla, Laura; Authier, Hélène; Maiuri, Maria Chiara; Morselli, Eugenia; Vitale, Ilio; Kepp, Oliver; Tasdemir, Ezgi; Galluzzi, Lorenzo; Shen, Si; Tailler, Maximilien; Delahaye, Nicolas; Tesniere, Antoine; De Stefano, Daniela; Younes, Aména Ben; Harp (Taylor and Francis Inc., 2010)
      Cells respond to stress by activating cytoplasmic mechanisms as well as transcriptional programs that can lead to adaptation or death. Autophagy represents an important cytoprotective response that is regulated by both ...
    • Criollo Céspedes, Alfredo; Niso-Santano, Mireia; Malik, Shoaib Ahmad; Michaud, Mickael; Morselli, Eugenia; Mariño, Guillermo; Lachkar, Sylvie; Arkhipenko, Alexander V.; Harper, Francis; Pierron, Gérard; Rain, Jean Christophe; Ninomiya-Tsuji, Jun; Fuentes, José M.; Lavandero González, Sergio (2011)
      Autophagic responses are coupled to the activation of the inhibitor of NF-κB kinase (IKK). Here, we report that the essential autophagy mediator Beclin 1 and TGFβ-activated kinase 1 (TAK1)-binding proteins 2 and 3 (TAB2 ...
    • Hernández Cáceres, María Paz; Cereceda, Karina; Hernández, Sergio; Li, Ying; Narro, Carla; Rivera, Patricia; Silva, Patricio; Ávalos, Yenniffer; Jara, Claudia; Burgos, Paulina; Toledo Valenzuela, Lilian; Lagos, Pablo; Cifuentes Araneda, Flavia; Pérez Leighton, Claudio; Bertocchi, Cristina; Clegg, Deborah J.; Criollo Céspedes, Alfredo; Tapia Rojas, Cheril; Burgos, Patricia V.; Morselli, Eugenia (Taylor & Francis, 2020)
      High-fat diet (HFD)-induced obesity is associated with increased cancer risk. Long-term feeding with HFD increases the concentration of the saturated fatty acid palmitic acid (PA) in the hypothalamus. We previously showed ...
    • Clegg, Deborah; Hevener, Andrea L.; Moreau, Kerrie L.; Morselli, Eugenia; Criollo Céspedes, Alfredo; Van Pelt, Rachael E.; Vieira Potter, Victoria J. (Oxford University Press, 2017-05)
      With increased life expectancy, women will spend over three decades of life postmenopause. The menopausal transition increases susceptibility to metabolic diseases such as obesity, diabetes, cardiovascular disease, and ...