Browsing by Author "14cc8a61-077e-45f3-a3b0-b65cd2346f45"

Now showing items 1-11 of 11

    • Adrenalectomy regulates apoptotic-associated genes in rat hippocampus 
      Greiner Gebauer, Monika Marcela; Cárdenas Muñoz, Sergio Patricio; Parra, C.; Bravo, Jaime F.; Avalos, Ana María; Paredes Vargas, Alfonso; Lara Peñaloza, Hernán; Fiedler Temer, Jenny (HUMANA PRESS INC, 2001-08)
      Morphological studies of granular neurons of the hippocampus have shown that adrenalectomy (ADX) induces the cell death of granular neurons, an effect prevented by corticosterone replacement. We addressed the hypothesis ...
    • Chronic stress triggers expression of immediate early genes and differentially affects the expression of ... 
      Pacheco Zapata, Aníbal; Aguayo, Felipe I.; Aliaga, Esteban; Muñoz, Mauricio; García Rojo, Gonzalo; Olave, Felipe A.; Parra Fiedler, Nicolás; García Pérez, Alexandra; Tejos Bravo, Macarena; Rojas, Paulina S.; Parra, Claudio S.; Fiedler Temer, Jenny (Frontiers media SA, 2017)
      Previous studies in rats have demonstrated that chronic restraint stress triggers anhedonia, depressive-like behaviors, anxiety and a reduction in dendritic spine density in hippocampal neurons. In this study, we compared ...
    • Corticosterone differentially regulates bax, bcl-2 and bcl-x mRNA levels in the rat hippocampus 
      Cárdenas Muñoz, Sergio Patricio; Parra, C.; Bravo, Jaime F.; Morales, P.; Lara Peñaloza, Hernán; Herrera-Marschitz Muller, Mario; Fiedler Temer, Jenny (ELSEVIER SCI IRELAND LTD, 2002-10-04)
      It has previously been shown that adrenalectomy (ADX) produces apoptosis in the granule cell of the dentate gyrus (DG), and that this effect is prevented by corticosterone replacement. Thus, we have investigated how this ...
    • Editorial: celebrating 40 years of the chilean society of pharmacology 
      Yévenes, Gonzalo E.; Bravo, Javier A.; Díaz Araya, Guillermo; Sotomayor Zárate, Ramón; Fiedler Temer, Jenny; Reyes Parada, Miguel; Fuentealba, Jorge (Frontiers Media, 2020)
    • An increased intraovarian synthesis of nerve growth factor and its low affinity receptor is a principal ... 
      Lara Peñaloza, Hernán; Dissen, G. A.; Leyton Canales, Víctor; Paredes Vargas, Alfonso; Fuenzalida Cruz, Héctor; Fiedler Temer, Jenny; Ojeda, Sergio R. (ENDOCRINE SOC, 2000-03)
      A form of polycystic ovary (PCO) resembling some aspects of the human PCO syndrome can be induced in rats by a single injection of estradiol valerate (EV). An increase in sympathetic outflow to the ovary precedes, by several ...
    • Matrix metalloproteinase 9 displays a particular time response to acute stress: variation in its levels and ... 
      Aguayo, Felipe I.; Pacheco Zapata, Aníbal; García Rojo, Gonzalo; Pizarro Bauerle, Javier; Doberti Martínez, Ana Valentina; Tejos Bravo, Macarena; García-Pérez, María A.; Rojas, Paulina S.; Fiedler Temer, Jenny (ACS Publications, 2018-05)
      A single stress exposure facilitates memory formation through neuroplastic processes that reshape excitatory synapses in the hippocampus, probably requiring changes in extracellular matrix components. We tested the hypothesis ...
    • Myelin basic protein stimulates plasminogen activation via tissue plasminogen activator following binding ... 
      Gonzàlez Gronow, Mario; Fiedler Temer, Jenny; Farías Gómez, Cristian; Wang, Fang; Ray, Rupa; Ferrell, Paul D.; Pizzo, Salvatore V. (Elsevier, 2017)
      Myelin basic protein (MBP) is a key component of myelin, the specialized lipid membrane that encases the axons of all neurons. Both plasminogen (Pg) and tissue-type plasminogen activator (t-PA) bind to MBP with high ...
    • Prenatal valproate treatment produces autistic-like behavior and increases metabotropic glutamate receptor ... 
      Peralta, Francisco; Fuentealba, Constanza; Fiedler Temer, Jenny; Aliaga, Esteban (Spandidos Publ. Ltd., 2016)
      Autism spectrum disorder (ASD) is a heterogeneous neurodevelopmental disorder characterized by deficits in social communication and social interaction, and repetitive and stereotypical patterns of behavior. Previously, a ...
    • Serotonin (5-HT) regulates neurite outgrowth through 5-HT1A and 5-HT7 receptors in cultured hippocampal neurons. 
      Rojas, P. S.; Neira, D.; Muñoz, Mauricio; Lavandero González, Sergio; Fiedler Temer, Jenny (Wiley, 2014)
      Serotonin (5-HT) production and expression of 5-HT receptors (5-HTRs) occur early during prenatal development. Recent evidence suggests that, in addition to its classical role as a neurotransmitter, 5-HT regulates neuronal ...
    • The ROCK inhibitor fasudil prevents chronic restraint stress-induced depressive-like behaviors and dendritic ... 
      García Rojo, Gonzalo; Fresno, Cristóbal; Vilches Peñaloza, Natalia; Díaz Véliz, Emma; Mora Gutiérrez, Sergio; Aguayo Abarca, Felipe; Pacheco Zapata, Aníbal; Parra Fiedler, Nicolás; Parra, Claudio; Rojas Domínguez, Paulina; Tejos Bravo, Macarena; Aliaga, Esteban; Fiedler Temer, Jenny (Oxford University Press, 2017-04-01)
      Background: Dendritic arbor simplification and dendritic spine loss in the hippocampus, a limbic structure implicated in mood disorders, are assumed to contribute to symptoms of depression. These morphological changes imply ...
    • What Do We Really Know About 5-HT1A Receptor Signaling in Neuronal Cells? 
      Rojas Domínguez, Paulina; Fiedler Temer, Jenny (Frontiers Media, 2016)
      Serotonin (5-HT) is a neurotransmitter that plays an important role in neuronal plasticity. Variations in the levels of 5-HT at the synaptic cleft, expression or dysfunction of 5-HT receptors may alter brain development ...