Now showing items 1-7 of 7

    • Mendoza Torres, Evelyn; Oyarzún, Alejandra; Mondaca Ruff, David; Azocar, Andrés; Chiong Lay, Mario; Castro, Pablo F.; Jalil Milad, Jorge; Lavandero González, Sergio; Ocaranza, María Paz (2015)
      The renin–angiotensin system (RAS) is a key component of cardiovascular physiology and homeostasis due to its influence on the regulation of electrolyte balance, blood pressure, vascular tone and cardiovascular remodeling. ...
    • González, Leticia; Novoa, Ulises; Moya, Jackeline; Gabrielli, Luigi; Jalil Milad, Jorge; García Nannig, Lorena; Chiong Lay, Mario; Lavandero González, Sergio; Ocaranza, María Paz (Elsevier Inc., 2018)
      © 2018 Elsevier Inc. Hypertension-induced cardiovascular and renal damage can be mediated by activation of the renin-angiotensin-aldosterone system. There are different factors beyond renin-angiotensin-aldosterone system ...
    • Ocaranza, Maria Paz; Lavandero González, Sergio; Jalil Milad, Jorge; Moya, Jaqueline; Pinto, Melissa; Novoa, Ulises; Apablaza, Felipe; González, Leticia; Hernández, Carol; Varas, Manuel; López, René; Godoy, Iván; Verdejo, Hugo; Chiong Lay, Mario (Lippincott Williams and Wilkins, 2010)
      Background: Angiotensin-(1-9) is present in human and rat plasma and its circulating levels increased early after myocardial infarction or in animals treated with angiotensin-converting enzyme inhibitor. However, the ...
    • Lavandero González, Sergio; Cartagena, Gastón; Guarda, Eduardo; Corbalán, Ramón; Godoy, Iván; Sapag Hagar, Mario; Jalil Milad, Jorge (Oxford University Press, 1993)
      Objective: The aim was to clarify the role of cyclic AMP dependent protein kinase (PKA) and changes in mechanical heart function during development of cardiac hypertrophy induced by volume overload. Methods: Protein and ...
    • Gálvez, Anita S.; Fiedler Temer, Jenny; Ocaranza, María Paz; Jalil Milad, Jorge; Lavandero González, Sergio; Díaz Araya, Guillermo (2005)
      Administration of the β-adrenergic agonist isoproterenol results in cardiac apoptosis, The effect of short-term β-adrenergic stimulation by isoproterenol on the activity of plasma, lung, and left ventricular (LV) angiotensin ...
    • Jalil Milad, Jorge; Piddo, Ana María; Cordova, Samuel; Chamorro, Gastón; Braun, Sandra; Jalil, Roberto; Vega, Jeanette; Jadue, Liliana; Lavandero González, Sergio; Lastra, Patricia (1999)
      The aim of this study was to estimate the prevalence of the different alleles of the angiotensin converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism and associated plasma ACE activity, as well as cardiac ...
    • Ebensperger González, Roberto; Acevedo, Erika; Meléndez, Jaime; Corbalán, Ramón; Acevedo, Mónica; Sapag Hagar, Mario; Jalil Milad, Jorge; Lavandero González, Sergio (Academic Press Inc., 1998)
      There is evidence that insulin-like growth factor-1 (IGF-1) plays a role in the development of left ventricular hypertrophy, but it is uncertain whether cardiac IGP-1 changes before or after hypertension is established, ...