Now showing items 1-20 of 42

    • Lemp Miranda, Else; Zanocco Loyola, Antonio; Günther Sapunar, Germán; Morales, Javier O. (2009)
      A high-performance liquid chromatography (HPLC) method for the determination of four different flavonoids, rutin, morin, quercetin, and 3-hydroxyflavone in dipalmitoylphosphatidylcholine (DPPC) liposome solutions has been ...
    • Montero, Guillermo; Günther Sapunar, Germán; Valdés Camus, Karina; Arriagada, Francisco; Morales, Javier O. (AOAC Int, 2018)
      In this work, we developed an HPLC method to simultaneously quantify and hence evaluate the stability, distribution, and antioxidant capacity of six isoflavones: genistein, genistin, daidzein, daidzin, glycitin, and biochanin ...
    • Arriagada, Francisco; Ugarte Núñez, Catalina; Günther Sapunar, Germán; Larraín Barth, María Angélica; Guarnizo Herrero, Víctor; Nonell, Santi; Morales Valenzuela, Javier (MDPI, 2020)
      The incorporation of pigments and natural polyphenols into inorganic matrices, resulting in a hybrid material that improves the resistance and chemical stability of the pigments and the antioxidant capacity of the materials, ...
    • Spada, Ramiro M.; Cepeda-Plaza, Marjorie; Gómez, María L.; Günther Sapunar, Germán; Jaque, Pablo; Pizarro, Nancy; Palacios, Rodrigo E.; Vega, Andrés (American Chemical Society, 2015)
      © 2015 American Chemical Society.Rhenium complexes are versatile molecular building blocks whose tunable photophysical properties are useful in diverse opto-related applications. Herein we report the synthesis and ...
    • Morales, Javier; Gai Hernández, María Nella; Günther Sapunar, Germán; Lemus, Igor; Lastra, Olga (2011)
      In this work, two simple and fast methods for the determination of candesartan cilexetil in pharmaceutical forms, having it as a sole drug, were developed and validated. Candesartan cilexetil is a prodrug hydrolyzed to ...
    • Pizarro, Nancy; Duque, Mario; Chamorro, Eduardo; Nonell, Santi; Manzur Saffie, Jorge; De la Fuente, Julio; Günther Sapunar, Germán; Cepeda Plaza, Marjorie; Vega, Andrés (American Chemical Society, 2015)
      © 2015 American Chemical Society. The spectroscopic, electrochemical, and photophysical properties of the new complex [P,N-{(C<inf>6</inf>H<inf>5</inf>)<inf>2</inf>(C<inf>5</i ...
    • Pizarro, Nancy; Duque, Mario; Chamorro, Eduardo; Nonell, Santi; Manzur Saffie, Jorge; Fuente Urrutia, Julio de la; Günther Sapunar, Germán; Cepeda Plaza, Marjorie; Vega, Andrés (American Chemical Society, 2015)
      The spectroscopic, electrochemical, and photophysical properties of the new complex [P,N-{(C6H5)(2)(C5H4N)-P}Re(CO)(3)Br] are reported. The UV-vis spectrum in dichloromethane shows an absorption maximum centered at 315 rim ...
    • Lissi Gervaso, Eduardo A.; Günther Sapunar, Germán; Zanocco Loyola, Antonio (AMER SOC PHOTOBIOLOGY, 1996-06)
      An equation is proposed for the evaluation of partition or association constants from fluorescence properties (such as spectrum shape or anisotropy) whose values are not linearly related to the solute distribution. The ...
    • Troncoso, N.; Sierra, H.; Carvajal, L.; Delpiano, P.; Günther Sapunar, Germán (ELSEVIER SCIENCE BV, 2005-12-23)
      An improved HPLC method is reported for the determination of rosemary's principal phenolic antioxidants, rosmarinic and carnosic acids, providing a fast and simultaneous determination for both of them by using a solid phase ...
    • Günther Sapunar, Germán; Berríos, Eduardo; Pizarro, Nancy; Valdés Camus, Karina; Montero, Guillermo; Arriagada, Francisco; Morales Montecinos, Javier (Public Library Science, 2015)
      In this work, the relationship between the molecular structure of three flavonoids (kaempferol, quercetin and morin), their relative location in microheterogeneous media (liposomes and erythrocyte membranes) and their ...
    • Yáñez Soto, Claudia; Günther Sapunar, Germán (Sociedad Chilena de Química, 2014)
      Differences in association constants values of cyclodextrin inclusion complexes can be found in the literature. Most of the times, different experimental conditions have been used leading to different results. This paper ...
    • Zanocco Loyola, Antonio; Lemp Miranda, Else; Günther Sapunar, Germán (1997)
      The sensitized photo-oxidation of boldine and its permethylated derivative, glaucine, has been studied in several solvents using steady-state kinetic methods. Values of kB, the total rate constant for the reaction between ...
    • Zanocco Loyola, Antonio; Günther Sapunar, Germán; Fuente, J. R. de la; Lemp Miranda, Else; Pizarro U., N. (1998)
      Detection of O,('A,) phosphorescence emission, A,,,, = 1270 nm, following laser excitation and steady-state competitive methods was employed to measure total rate constants, k,, for the reactions of the diuretic furosemide, ...
    • Prado, Gaspar; Ibañez, María Belén; Acosta, Alison; Chamorro, Eduardo; Hermosilla Ibañez, Patricio; Günther Sapunar, Germán; Pizarro, Nancy; Vega, Andrés (Elsevier, 2017)
      The reaction of [P,N-{(C6H5)(2)(C5H4N)P}Re(CO)(3)Br] (RePNBr) with silver triflate leads to the complex [P,N-{(C6H5)(2)(C5H4N)P}Re(CO)(3)(O-CF3SO3)] (RePNTfO) with moderate yield. This new P,N-Re-I triflate compound contains ...
    • Sánchez, Susana A.; Sandoval, Catalina; Günther Sapunar, Germán (Cell Press, 2016)
    • Sánchez, Susana A.; Günther Sapunar, Germán; Tricerri, Maria A.; Gratton, Enrico (2011)
      Methyl-β-cyclodextrins (MβCDs) are molecules that are extensively used to remove and to load cholesterol (Chol) from artificial and natural membranes; however, the mechanism of Chol extraction by MβCD from pure lipids or ...
    • Arriagada, Francisco; Correa Briones, Olosmira; Günther Sapunar, Germán; Nonell, Santi; Mura Mardones, Francisco; Olea Azar, Claudio; Morales Montecinos, Javier (Public Library Science, 2016)
      Morin (2' A, 3, 4' , 5,7-pentahydroxyflavone) is a flavonoid with several beneficial health effects. However, its poor water solubility and it sensitivity to several environmental factors avoid its use in applications like ...
    • Günther Sapunar, Germán; Lemp Miranda, Else; Zanocco Loyola, Antonio (SOCIEDAD CHILENA DE QUIMICA, 2000-12)
      Time resolved near IR luminescence detection of singlet oxygen, O-2((1)Delta (g)), and steady-state photolysis experiments were performed to study in detail limitations and approaches involved when 9,10-dimethylanthracene ...
    • Pizarro Urzúa, Nancy A.; Günther Sapunar, Germán; Núñez Vergara, Luis (ELSEVIER SCIENCE, 2007-06-10)
      A different photophysical and photochemical behavior has been found between two second generation antihypertensive 1,4-dihydropyitidines (1,4-DHPs), felodipine and nimodipine. While nimodipine was observed as being more ...
    • Valdés Camus, Karina; Morales, Javier; Rodríguez, Lennin; Günther Sapunar, Germán (Future Medicine Ltd, 2016-12)
      Ursolic, oleanolic and betulinic acids are representative pentacyclic triterpenoids found in various plants and fruits. Despite having marked antitumor potentials, the very poor water solubility of these triterpenes hinders ...