Now showing items 1-2 of 2

    • In vitro and in vivo antitrypanosomatid activity of 5-nitroindazoles 

      Boiani, Lucia; Gerpe, Alejandra; Arán, Vicente; Torres de Ortiz, Susana; Serna, Elva; Vera de Bilbao, Ninfa; Sanabria, Luis; Yaluff, Gloria; Nakayama, Héctor; Rojas de Arias, Antonieta; Maya Arango, Juan; Morello, J.; Cerecetto, Hugo; González, Mercedes (2009)
      Previously, we have identified a series of 5-nitroindazoles with good antiprotozoal activities, against Trypanosoma cruzi epimastigotes and Trichomonas vaginalis. Most of them have shown very low unspecific toxicity on ...
    • Studies on quinones. Part 36. Synthesis and trypanocidal activity of 2-alkoxycarbonylbenzo[b]thiophene-4,7-quinones 

      Pessoa, D.; Valderrama Guerrero, Jaime Adolfo; Olmos, María G.; Espinoza, Omar; Pessoa Mahana, Hernán; Rojas de Arias, Antonieta; Nakayama, Héctor; Torres, Susana; Miret, Jorge (FREUND PUBLISHING HOUSE LTD, 2002)
      A series of 2-alkoxycarbonylbenzo[b]thiophene-4,7-quinones (11-15), prepared from the corresponding acid 5, were tested in vitro against trypomastigote form of Trypanosome cruzi. The influence of the lypophilia and oxidant ...