Browsing by Author "7669abc9-de0a-4699-9636-67d72e4221c7"

Now showing items 1-5 of 5

    • Solvent-free microwave-promoted Michael addition of aza-nucleophiles to benzo[b] thiophen-2-yl-2-propenone 
      Pessoa Mahana, Hernán; González, Marcos; González, Marcelo; Pessoa, D.; Araya Maturana, Ramiro; Ron Higuera, Nadia Betsabé; Saitz Barría, Claudio (ARKAT USA INC, 2009)
      A series of Michael adducts (5-11) have been synthesized with good yields under solvent-free microwave conditions. Aliphatic and aromatic amines utilized as Michael donors reacted with 1-(4,7-dimethoxybenzo[b] thiophen-2 ...
    • Spectral and Kinetic Study of 3-Methylquinoxalin-2-ones Photoreduced by Amino Acids: N-Phenylglycine Radical ... 
      Fuente Urrutia, Julio de la; Cañete, Álvaro; Carathanassis, Natalia; Bernazar, Luan; Saitz Barría, Claudio; Díaz Hernández, Dafne (Amer Chemical Society, 2016)
      Transient intermediates were identified in the photoreduction of 3-methylquinoxalin-2-one derivatives by N-phenylglycine, NPG, and N-acetyltryptophan, NAT. For both reductants it can be postulated a sequence of reaction ...
    • Synthesis of 2-benzothienyl carbonyl 4-arylpiperazines as novel delavirdine analogs 
      Pessoa Mahana, Hernán; Acevedo Ramos, Armando Rodrigo; Saitz Barría, Claudio; Araya Maturana, Ramiro; Pessoa, D. (TAYLOR & FRANCIS INC, 2007)
      A novel series of 2-benzothienyl carbonyl arylpiperazines (6a-f) was synthesized as potential HIV nonnucleoside reverse transcriptase inhibitors (NNRTIs). Preparation of the derivatives was performed by reacting benzo[b]thiophene ...
    • Synthesis of conformationally restricted N-{4-[4-(4,7-Dimethoxy-Benzo[b]Thiophene-2-Carbonyl)-1-Piperazin ... 
      Pessoa Mahana, Hernán; González Lira, Christian Guillermo; Araya Maturana, Ramiro; Saitz Barría, Claudio; Pessoa, D. (SOC CHILENA QUIMICA, 2009-06)
      New benzothiophene arylpiperazine derivatives 7 (a-1) were synthesized as potential serotoninergic agents with 5-HT1A receptor affinity. Preparation of the derivatives was performed by reaction of 1-(4-aminophenyl)-4-[(4 ...
    • A synthethic overview of new molecules with 5-HT 1A binding affinities 
      Pessoa Mahana, Hernán; Araya Maturana, Ramiro; Saitz Barría, Claudio; Pessoa, D. (Bentham Science Publishers, Ltd, 2003)
      The present review discusses the synthetic strategies of new ligands exhibiting mainly 5-HT1A binding affinities. Specifically we focused our attention in the synthesis of compounds structurally telated to arylpiperazine, ...