Browsing by Author "Alzate Morales, Jans"
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Alzate Morales, Jans (Universidad de Chile, 2006)En esta tesis se presentan varias aproximaciones computacionales aplicadas al estudio de las interacciones proteína-ligando en el sistema enzimático CDK2/Ciclina A (Cyclin Dependent Kinase 2/Cyclin A). Los métodos ...
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Rojo, Leonel E.; Alzate Morales, Jans; Saavedra, Iván N.; Davies, Peter; Maccioni Baraona, Ricardo (IOS Press, 2010)We describe the interactions of two benzimidazole derivatives, astemizole (AST) and lansoprazole (LNS), with anomalous aggregates of tau protein (neurofibrillary tangles). Interestingly, these compounds, with important ...