Browsing by Author "Fierro, Angélica"

Now showing items 1-2 of 2

    • Methylpiperidinium Iodides as novel antagonists for alpha 7 nicotinic acetylcholine receptors 
      López Villa, Jhon; García Colunga, Jesús; Pérez, Edwin G.; Fierro, Angélica (Frontiers Media, 2018)
      The alpha 7 nicotinic acetylcholine receptor (nAChR) is expressed in neuronal and non-neuronal cells and is involved in several physiopathological processes, and is thus an important drug target. We have designed and ...
    • Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole ... 
      Pessoa Mahana, Hernán; González Lira, Christian; Fierro, Angélica; Zapata Torres, Gerald Amilcar; Pessoa Mahana, Carlos David; Ortiz Severin, Javiera; Iturriaga-Vásquez, Patricio; Reyes Parada, Miguel; Silva Matus, Paul; Saitz Barría, Claudio; Araya Maturana, Ramiro (Elsevier, 2013)
      A series of 3-(3-(4-(3-(1H-indol-3-yl)propyl)piperazin-1-yl)propyl)-1H-indole derivatives (3a–d and 5a– f) as homo- and hetero-bis-ligands, were synthesized and evaluated for in vitro affinity at the serotonin transporter ...