Browsing by Author "b9d2525d-fa4b-4139-8ce1-847e63759f97"

Now showing items 1-3 of 3

    • A candidate gene approach of the calcineurin pathway to identify variants associated with clinical outcomes ... 
      Pouché, Lucie; Koitka, Matthias; Stojanova, Jana; Woillard, Jean Baptiste; Monchaud, Caroline; Villeneuve, Claire; Essig, Marie; Abraham, Julie; Le Meur, Yannick; Rerolle, Jean Phillippe; Kamar, Nassim; Rostaing, Lionel; Merville, Pierre; Gandia, Peggy; Bouchet, Stepha (Future Medicine Ltd., 2016)
      © 2016 Future Medicine Ltd.Aim: To investigate the potential influence of variants in genes involved in the calcineurin pathway on the efficacy and toxicity of calcineurin inhibitors in renal transplantation. Materials & ...
    • Can pharmacogenetics explain efficacy and safety of cisplatin pharmacotherapy? 
      Roco, ángela; Cayún, Juan; Contreras, Stephania; Stojanova, Jana; Quiñones, Luis (Frontiers Media S.A., 2014)
      © 2014 Roco, Cayún, Contreras, Stojanova and Quiñones.Several recent pharmacogenetic studies have investigated the variability in both outcome and toxicity in cisplatin-based therapies. These studies have focused on the ...
    • Characterization of the CYP2D6 drug metabolizing phenotypes of the Chilean mestizo population through ... 
      Varela, Nelson; Quiñones Sepúlveda, Luis; Stojanova, Jana; Garay, Joselyn; Cáceres, Dante; Cespedes, Silvia; Sasso, Jaime; Miranda, Carla (Elsevier, 2015-11)
      We tested the influence of four polymorphisms and gene duplication in CYP2D6 on in vivo enzyme activity in a Chilean mestizo population in order to identify the most relevant genetic profiles that account for observed ...