Browsing by Author "El Kholy, Mona"

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    • Impact of CYP2C19 genetic polymorphisms on voriconazole dosing and exposure in adult patients with invasive ... 
      Lamoureux, Fabien; Duflot, Thomas; Woillard, Jean-Baptiste; Metsu, David; Pereira, Tony; Compagnon, Patricia; Morisse-Pradierd, Hélène; El Kholy, Mona; Thiberville, Luc; Stojanova, Jana; Thuillez, Christian (Elsevier, 2016)
      Voriconazole (VCZ) use is limited by its narrow therapeutic range and significant interpatient variability in exposure. This study aimed to assess (i) the impact of CYP2C19 genotype on VCZ exposure and (ii) the doses ...