Browsing by Author "Montecinos, Luis"
Now showing items 1-3 of 3
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Sánchez, Gina; Fernández, Carolina; Montecinos, Luis; Domenech Lira, Raúl; Donoso Laurent, Paulina (2011)Cardioprotection by preconditioning is a central issue of current research on heart function. Several reports indicate that preventing the assembly and opening of the mitochondrial permeability transition pore (mPTP) ...
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Ronjat, Michel; Finkelstein, José Pablo; Llanos Vidal, Paola; Montecinos, Luis; Bichraoui, Hicham; Waard, Michel De; Hidalgo Tapia, María Cecilia; Bull Simpfendorfer, Ricardo (Elsevier, 2013)The scorpion toxin maurocalcine acts as a high affinity agonist of the type-1 ryanodine receptor expressed in skeletal muscle. Here, we investigated the effects of the reducing agent dithiothreitol or the oxidizing reagent ...
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Donoso Laurent, Paulina; Finkelstein Muñoz, José Pablo; Montecinos, Luis; Said, Matilde; Sánchez, Gina; Vittone, Leticia; Bull Simpfendorfer, Ricardo (Elsevier, 2014)The response of ryanodine receptor (RyR) channels to cytoplasmic free calcium concentration ([Ca2+]) is redox sensitive. Here, we report the effects of a mild oxidative stress on cardiac RyR (RyR2) channels in ...