Browsing by Author "Ojeda, Jorge"

Now showing items 1-2 of 2

    • ALS-linked protein disulfide isomerase variants cause motor dysfunction 
      Woehlbier, Ute; Colombo Flores, Alicia; Saaranen, Mirva J.; Pérez, Viviana; Ojeda, Jorge; Bustos, Fernando J.; Andreu, Catherine; Torres, Mauricio; Valenzuela, Vicente; Medinas Bilches, Danilo; Rozas, Pablo; Vidal, René L.; López González, Rodrigo; Salameh, Johnny; Fernández Collemann, Sara; Muñoz, Natalia; Matus, Soledad; Armisen Yáñez, Ricardo; Sagredo, Alfredo; Palma, Karina; Irrázabal, Thergiory; Almeida, Sandra; González Pérez, Paloma; Campero, Mario; Gao, Fen-Biao; Henny, Pablo; Van Zundert, Brigitte; Ruddock, Lloyd W.; Concha, Miguel L.; Henríquez, Juan P.; Brown, Robert H.; Hetz Flores, Claudio (Wiley-Blackwell, 2016)
      Disturbance of endoplasmic reticulum (ER) proteostasis is a common feature of amyotrophic lateral sclerosis (ALS). Protein disulfide isomerases (PDIs) are ER foldases identified as possible ALS biomarkers, as well as ...
    • Protein disulfide isomerase ERp57 protects early muscle denervation in experimental ALS 
      Rozas Rojas, Pablo Sebastián; Pinto, Cristina; Martínez Traub, Francisca José; Díaz Hinojosa, Rodrigo Ignacio; Pérez, Viviana; Becerra, Daniela; Ojeda, Patricia; Ojeda, Jorge; Wright, Madison T.; Mella, Jéssica; Plate, Lars; Henríquez, Juan Pablo; Hetz Flores, Claudio Andrés; Bilches Medinas, Danilo (BMC, 2021)
      Amyotrophic lateral sclerosis (ALS) is a progressive fatal neurodegenerative disease that affects motoneurons. Mutations in superoxide dismutase 1 (SOD1) have been described as a causative genetic factor for ALS. Mice ...