Browsing by Author "Sasso Aguirre, Jaime Alfredo"

Now showing items 1-7 of 7

    • Aspectos farmacocinéticos a considerar en el tratamiento farmacológico de niños en comparación con adultos 
      Saavedra Saavedra, Iván; Quiñones Sepúlveda, Luis; Sasso Aguirre, Jaime Alfredo; Miranda Melo, Carla Estefanía; Saavedra B., Mónica; Roco Arriagada, Angela Margarita (2010)
      Los avances en farmacología clínica muestran que la edad afecta considerablemente la farmacocinética de los medicamentos, por lo tanto, sus efectos en lactantes y niños pueden diferir a los producidos en adultos, aún cuando ...
    • Bioequivalence of Acenocoumarol in Chilean Volunteers: an Open, Randomized, Double-Blind, Single-Dose, ... 
      Sasso Aguirre, Jaime Alfredo; Carmona, P.; Quiñones Sepúlveda, Luis; Ortiz Olcay, Mario; Tamayo Carrillo, Evelyn; Varela Figueroa, Nelson; Cáceres Lillo, Dante; Saavedra Saavedra, Iván (2012)
      The aim of this study was to compare the bioavailability of an oral formulation of the coumarin derivative-vitamine K antagonist acenocoumarol (Acebron TM 4 mg, Test) with the reference formulation (Neo-Sintrom TM 4 ...
    • Estudio de biodisponibilidad relativa entre dos formulaciones orales de micofenolato mofetilo en voluntarios sanos 
      Saavedra Saavedra, Iván; Sasso Aguirre, Jaime Alfredo; Quiñones Sepúlveda, Luis; Saavedra B., Mónica; Gaete González, Leonardo; Boza T., Ignacio; Carvajal H., Cristóbal; Soto Labbé, Jorge (2011)
      Background: The bioequivalence of different formulations of a same pharmaceutical product must be tested empirically. Aim: To evaluate the relative bioavailability for an oral formulation of mycophenolate mofetil (MMF) ...
    • Farmacocinética de medicamentos de uso pediátrico, visión actual 
      Saavedra Saavedra, Iván; Quiñones Sepúlveda, Luis; Saavedra B., Mónica; Sasso Aguirre, Jaime Alfredo; León, Jorge; Roco A., Angela (2008)
      Pharmacokinetics corresponds to the branch of pharmacology that studies the absorption, distribution, biotransformation and excretion of drugs in the body, in order to proportionate a reference line for interpretation ...
    • Influence of CYP3A4/5 Polymorphisms in the pharmaconetics of levonorgestrel: a pilot study 
      Moreno, Iván; Quiñones Sepúlveda, Luis; Catalán, Johanna; Miranda Melo, Carla Estefanía; Roco Arriagada, Ángela Margarita; Sasso Aguirre, Jaime Alfredo; Tamayo Carrillo, Evelyn; Cáceres Lillo, Dante; Tchernitchin Varlamov, Andrés; Gaete González, Leonardo; Saavedra Saavedra, Iván (2012)
      Introduction. Levonorgestrel a synthetic progestagen used for endometriosis, dysmenorrhea and emergency contraception, is quickly and completely absorbed in the digestive tract. levonorgestrel is predominantly metabolised ...
    • Relationship of cortisol levels and genetic polymorphisms to antidepressant response to placebo and fluoxetine ... 
      Ventura Juncá, Raúl; Symon Maturana, Adriana; López, Pamela; Fiedler Temer, Jenny; Rojas Castillo, María Graciela; Heskia Vergara, Cristóbal; Lara, Pamela; Marín, Felipe; Guajardo, Viviana; Araya, A. Verónica; Sasso Aguirre, Jaime Alfredo; Herrera Cisterna, Luisa (BioMed Central, 2014)
      Background: Increased cortisol levels and genetic polymorphisms have been related to both major depressive disorder and antidepressant treatment outcome. The aim of this study is to evaluate the relationship between circadian ...
    • Relative bioavailability study with two oral formulations of topiramate using a validated UPLC-MS/MS method 
      Saavedra Saavedra, Iván; Tamayo Carrillo, Evelyn; Gamboa, A.; Sasso Aguirre, Jaime Alfredo; Varela Figueroa, Nelson; Moreno, Iván; Marchant Lavín, Dafne; Cáceres Lillo, Dante; Quiñones Sepúlveda, Luis (2010)
      Changes in bioavailability of anticonvulsant drugs such as topiramate may cause loss of or worsened seizure control. Thus, the purpose of this study was to evaluate, in a double-blind crossover design, the bioavailability ...