Browsing by Author "Soto, Lilian"

Now showing items 1-4 of 4

    • B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, ... 
      Catalán Martina, Diego; Aravena, Octavio; Sabugo, Francisca; Wurmann, Pamela; Soto, Lilian; Kalergis, Alexis M.; Cuchacovich Turteltaub, Miguel; Aguillón Gutiérrez, Juan Carlos (2010)
      Introduction: Several molecules help preserve peripheral B cell tolerance, but when altered, they may predispose to autoimmunity. This work studied the expression of the costimulatory molecule CD86 and the inhibitory ...
    • Immunosuppressive Mechanisms of Regulatory B Cells 
      Catalán Martina, Diego Francisco; Mansilla, Miguel Andrés; Ferrier Espósito, Ashley Andrés; Soto, Lilian; Oleinika, Kristine; Aguillón Gutiérrez, Juan Carlos; Aravena, Octavio (Frontiers Media, 2021)
      Regulatory B cells (Bregs) is a term that encompasses all B cells that act to suppress immune responses. Bregs contribute to the maintenance of tolerance, limiting ongoing immune responses and reestablishing immune ...
    • Skewing dendritic cell differentiation towards a tolerogenic state for recovery of tolerance in rheumatoid ... 
      Schinnerling, Katina; Soto, Lilian; García González, Paulina; Catalán Martina, Diego; Aguillón Gutiérrez, Juan Carlos (Elsevier, 2015)
      To date, the available options to treat autoimmune diseases such as rheumatoid arthritis (RA) include traditional corticoids and biological drugs, which are not exempt of adverse effects. The development of cellular ...
    • Systemic sclerosis patients present alterations in the expression of molecules involved in B-cell regulation 
      Soto, Lilian; Ferrier, Ashley; Aravena Madariaga, Octavio; Fonseca, Elianet; Berendsen, Jorge; Biere, Andrea; Bueno, Daniel; Ramos, Verónica; Aguillón Gutiérrez, Juan Carlos; Catalán Martina, Diego (Frontiers Media, 2015)
      The activation threshold of B cells is tightly regulated by an array of inhibitory and activator receptors in such a way that disturbances in their expression can lead to the appearance of autoimmunity. The aim of this ...