Browsing by Author "Varela Figueroa, Nelson Miguel Edgardo"

Now showing items 1-6 of 6

    • A new insight for the identification of oncogenic variants in breast and prostate cancers in diverse human ... 
      Varela Figueroa, Nelson Miguel Edgardo; Guevara Ramírez, Patricia; Acevedo Castillo, Cristian Andrés; Zambrano Coloma, Tomas Andres; Armendáriz Castillo, Isaac; Guerrero, Santiago; Quiñones, Luis A.; López Cortés, Andrés (Frontiers Media, 2021)
      Background: Breast cancer (BRCA) and prostate cancer (PRCA) are the most commonly diagnosed cancer types in Latin American women and men, respectively. Although in recent years large-scale efforts from international consortia ...
    • In silico analyses of immune system protein interactome network, single-cell RNA sequencing of human tissues, ... 
      López Cortés, Andrés; Guevara Ramírez, Patricia; Kyriakidis, Nikolaos C.; Barba Ostria, Carlos; León Cáceres, Ángela; Guerrero, Santiago; Ortiz Prado, Esteban; Munteanu, Cristian R.; Tejera, Eduardo; Cevallos Robalino, Doménica; Gómez Jaramillo, Ana María; Simbaña Rivera, Katherine; Granizo Martínez, Adriana; Pérez M., Gabriela; Moreno, Silvana; García Cárdenas, Jennyfer M.; Zambrano, Ana Karina; Pérez Castillo, Yunierkis; Cabrera Andrade, Alejandro; Puig San Andrés, Lourdes; Proaño Castro, Carolina; Bautista, Jhommara; Quevedo, Andreina; Varela Figueroa, Nelson Miguel Edgardo; Quiñones Sepúlveda, Luis Abel; Paz y Miño, César (Frontiers Media, 2021)
      Background: There is pressing urgency to identify therapeutic targets and drugs that allow treating COVID-19 patients effectively. Methods: We performed in silico analyses of immune system protein interactome network, ...
    • NOD1 rs2075820 (p.E266K) polymorphism is associated with gastric cancer among individuals infected with ... 
      González Hormazábal, Patricio; Peláez, Diana; Musleh Katan, Maher Elías; Bustamante, Marco; Stambuk Mayorga, Juan Antonio; Pisano, Raúl; Valladares Hernández, Héctor; Lanzarini Sobrevía, Enrique Giovani; Chiong, Héctor; Suazo Sanhueza, José Lorenzo; Quiñones Sepúlveda, Luis Abel; Varela Figueroa, Nelson Miguel Edgardo; Castro, Gonzalo; Jara Sosa, Lilian Elena; Berger, Zoltan (Sociedad de Biología de Chile, 2021)
      BackgroundHelicobacter pylori is detected by pathogen recognition receptors including toll-like receptors (TLR) and nucleotide-binding oligomerization domain (NOD)-like receptors, eliciting an innate immune response against ...
    • Pharmacogenetic associations between atazanavir/UGT1A1*28 and efavirenz/rs3745274 (CYP2B6) account for ... 
      Poblete Astroza, Daniela Lorena; Bernal, Fernando; Llull Morchio, Gabriel Eduardo; Archiles Olivares, Sebastián Gabriel; Vásquez, Patricia; Chanqueo Cornejo, Leonardo Andrés; Soto, Nicole; Lavanderos de Paz, María Angélica; Quiñones Sepúlveda, Luis Abel; Varela Figueroa, Nelson Miguel Edgardo (Frontiers Media, 2021)
      Background: Efavirenz (EFV), a non-nucleoside reverse transcriptase inhibitor, and atazanavir (ATV), a protease inhibitor, are drugs widely used in antiretroviral therapy (ART) for people living with HIV. These drugs have ...
    • Pharmacogenetics–based preliminary algorithm to predict the incidence of infection in patients receiving ... 
      Martínez Olguín, Matías Fernando; Alveal, Enzo; Soto, Tomás Gonzalo; Bustamante, Eva I.; Ávila Oesterle, Fernanda; Bangdiwala, Shrikant Ishver; Flores, Ivonne; Monterrosa, Claudia; Morales, Ricardo; Varela Figueroa, Nelson Miguel Edgardo; Fohner, Alison E.; Quiñones Sepúlveda, Luis Abel (Frontiers Media, 2021)
      Introduction: Infections in hematological cancer patients are common and usually lifethreatening; avoiding them could decrease morbidity, mortality, and cost. Genes associated with antineoplastics’ pharmacokinetics or ...
    • Smartphone screen testing, a novel pre-diagnostic method to identify SARS-CoV- 2 infectious individuals 
      Young, Rodrigo M.; Solis, Camila J.; Barriga Fehrman, Andrés; Abogabir, Carlos; Thadani, Álvaro R.; Labarca, Mariana; Bustamante, Eva; Tapia, Cecilia V.; Sarda, Antonia G.; Sepúlveda, Francisca; Pozas, Nadia; Cerpa, Leslie C; Lavanderos, María A.; Varela Figueroa, Nelson Miguel Edgardo; Santibáñez, Álvaro; Sandino, Ana M.; Reyes López, Felipe; Dixon, Garth; Quiñones Sepúlveda, Luis Abel (Elife Sciences Publications, 2021)
      The COVID-19 pandemic will likely take years to control globally, and constant epidemic surveillance will be required to limit the spread of SARS-CoV-2, especially considering the emergence of new variants that could ...