Instituto de Nutrición y Tecnología de los Alimentos: Recent submissions
Now showing items 1-20 of 705
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Obesity and Related Metabolic Biomarkers and Its Association with Serum Levels of Estrogen in Pre-pubertal Chilean Girls
(Taylor & Francis, 2020)Purpose: Recent reports show that girls with higher body mass index (BMI) have an earlier puberty onset (thelarche). It has been suggested that earlier puberty is a consequence of higher levels of estrogen due to increased ... -
Fatty acid and lipid metabolism in liver of pregnant mice and their offspring is influenced by unbalanced folates/vitamin B12 diets
(Elsevier, 2020)Micronutrients (folates and vitamin B12) and long chain polyunsaturated fatty acids (LC-PUFAs) are linked through the one carbon cycle. We studied the effects of pre and postnatal high FA/low B12 diets (HFLB12) on hepatic ... -
Evaluating the impact of Chile’s marketing regulation of unhealthy foods and beverages: preschool and adolescent children’s changes in exposure to food advertising on television
(Cambridge University Press, 2020)Objective: To evaluate the effects of Chile's 2016 regulation restricting child-directed marketing of products high in energy, saturated fats, sodium and sugars on reducing children's exposure to 'high-in' television food ... -
The CatSper channel is present and plays a key role in sperm motility of the Atlantic salmon (Salmo salar)
(Elsevier, 2020)Among all the Ca2+ channels, CatSper channels have been one of the most studied in sperm of different species due to their demonstrated role in the fertilization process. In fish sperm, the calcium channel plays a key role ... -
Low nanomolar concentrations of a quercetin oxidation product, which naturally occurs in onion peel, protect cells against oxidative damage
(Elsevier, 2020)The occurrence of the quercetin oxidation metabolite 2-(3,4-dihydroxybenzoyl)-2,4,6-trihydroxy-3(2H)-benzofuranone (BZF), whose antioxidant potency is notably higher than the antioxidant potency of quercetin, was investigated ... -
In vitro study of the protective effect of manganese against vanadium mediated nuclear and mitochondrial DNA damage
(Elsevier, 2020)We aimed to study the effect of vanadium(V) exposure on cell viability, nuclear DNA (nDNA) and mitochondrial DNA (mtDNA) and to elucidate if these effects can be reverted by co-exposure to V and manganese (Mn). HepG2 cells ... -
Uncoupled inflammatory, proliferative, and cytoskeletal responses in senescent human gingival fibroblasts
(Wiley, 2020)Background and objective: Aging is characterized by a decline in tissue structure and function that may be explained by the development of cellular senescence. However, the acquisition of specific phenotypic responses in ... -
Cardiometabolic health in offspring of women with PCOS compared to healthy controls: a systematic review and individual participant data meta-analysis
(Oxford Unv Press, 2020)BACKGROUND: Women diagnosed with polycystic ovary syndrome (PCOS) suffer from an unfavorable cardiometabolic risk profile, which is already established by child-bearing age. OBJECTIVE AND RATIONALE: The aim of this ... -
A restricted spectrum of missense KMT2D variants cause a multiple malformations disorder distinct from Kabuki syndrome
(Nature, 2020)Purpose To investigate if specific exon 38 or 39 KMT2D missense variants (MVs) cause a condition distinct from Kabuki syndrome type 1 (KS1). Methods Multiple individuals, with MVs in exons 38 or 39 of KMT2D that encode a ... -
Evaluation of the stability of fatty acids in erythrocytes from human umbilical cord
(Wiley, 2020)The interest in the amount of polyunsaturated fatty acids (PUFA) in the umbilical cord blood (UCB) is increasing, but the stability of erythrocyte PUFA in these samples during storage and washing of the erythrocytes has ... -
Melatonin triggers metabolic and gene expression changes leading to improved quality traits of two sweet cherry cultivars during cold storage
(Elsevier, 2020)Sweet cherry is a valuable non-climacteric fruit with elevated phytonutrients, whose fruit quality attributes are prone to rapid deterioration after harvest, especially peel damage and water loss of stem. Here the metabolic ... -
Quantification and Distribution of Omega-3 Fatty Acids in South Pacific Fish and Shellfish Species
(MDPI, 2020)Fatty acid composition and distribution in edible species of fish and shellfish captured in the South Pacific were studied, with a focus on n-3 long-chain polyunsaturated fatty acids (n-3 LCPUFA). Fatty acids were quantified ... -
Science and health policies to tackle chronic diseases in Chile
(Elsevier, 2020)Chile has experienced rapid epidemiological transitions characterized by decreasing infant mortality, population aging, and a shift towards obesity with an increase in noncommunicable diseases (NCDs). Today, tobacco, ... -
Dietary gluten as a conditioning factor of the gut microbiota in celiac disease
(Oxford University Press, 2020)The gut microbiota plays a relevant role in determining an individual's health status, and the diet is a major factor in modulating the composition and function of gut microbiota. Gluten constitutes an essential dietary ... -
Association between chronic health conditions and quality of life in rural teachers
(Frontiers Media, 2020)Aim The school teacher profession has been reported to be associated with an increased rate of health problems that can affect the quality of life (QoL) of teachers. However, there is little information about rural teachers. ... -
Academically oriented activity breaks for first-grade chilean students: development and pilot testing effectiveness
(Sage, 2020)We developed and pilot tested the effectiveness of a physically active academic program, Active Breaks (AB), whose objective is to increase school time moderate/vigorous physical activity (MVPA) among first graders, through ... -
Factors related to depressive symptoms and self-reported diagnosis of depression in community-dwelling older Chileans: A national cross-sectional analysis
(Wiley, 2020)Aim The aims of this study were to describe the prevalence of screening-positive depression and to identify the frequency and factors related to self-reported depression diagnosis in people with screen-positive ... -
Biological Redox Impact of Tocopherol Isomers Is Mediated by Fast Cytosolic Calcium Increases in Living Caco-2 Cells
(MDPI, 2020)Most of the biological impacts of Vitamin E, including the redox effects, have been raised from studies with alpha-tocopherol only, despite the fact that tocopherol-containing foods carry mixed tocopherol isomers. Here, ... -
Transcriptomic changes of piscirickettsia salmonis during intracellular growth in a salmon macrophage-like cell line
(Frontiers Media, 2020)Piscirickettsia salmonis is the causative agent of Piscirickettsiosis, a systemic infection of salmonid fish species. P. salmonis infects and survives in its host cell, a process that correlates with the expression of ...
