Recent Submissions

  • Helicobacter pylori outer membrane vesicles and extracellular vesicles from helicobacter pylori-infected cells in gastric disease development 

    González, María Fernanda; Díaz, Paula; Sandoval Bórquez, Alejandra; Herrera, Daniela; Geoffery Quest, Andrew (MDPI, Suiza, 2021)
    Extracellular vesicles (EVs) are cell-derived vesicles important in intercellular communication that play an essential role in host-pathogen interactions, spreading pathogen-derived as well as host-derived molecules during ...
  • Hypomyelination and Congenital Cataract: Identification of a Novel likely pathogenic c.414+1G>A in FAM126A gene Variant 

    Troncoso, Mónica; Balut Oyarzún, Fernanda; Witting Enríquez, Scarlet; Rubilar Parra, Carla; Carrera, Jorge; Cartes, Fabiola; Herrera Cisterna, Luisa (Wiley, 2021)
    It is key to expand the differential diagnosis and consider possible genetic etiologies on a patient with congenital cataracts associated with clinical features, such as leukodystrophy or polyneuropathy.
  • Impact of bacterial metabolites on gut barrier function and host immunity: a focus on bacterial metabolism and its relevance for intestinal inflammation 

    Gasaly, Naschla; de Vos, Paul; Hermoso, Marcela (Frontiers Media, 2021)
    The diverse and dynamic microbial community of the human gastrointestinal tract plays a vital role in health, with gut microbiota supporting the development and function of the gut immune barrier. Crosstalk between ...
  • Impact of Maternal Obesity on the Metabolism and Bioavailability of Polyunsaturated Fatty Acids during Pregnancy and Breastfeeding 

    Álvarez, Daniela; Muñoz, Yasna; Ortiz, Macarena; Maliqueo Yevilao, Manuel; Chouinard Watkins, Raphael; Valenzuela, Rodrigo (MDPI, 2021)
    Prenatal and postnatal development are closely related to healthy maternal conditions that allow for the provision of all nutritional requirements to the offspring. In this regard, an appropriate supply of fatty acids (FA), ...
  • Atrofia monomiélica distal de extremidad superior. Caso clínico 

    Matamala Capponi, José Manuel; Cea Muñoz, Gabriel; Salinas Ríos, Rodrigo; Vidal Téllez, Aarón; López, Ingeborg; Marileo, Roberto; Stuardo, Andrés (Sociedad Médica de Santiago, Chile, 2021)
    Monomelic amyotrophy, also known as Hirayama disease, is a rare lower motor neuron syndrome due to localized lower motor neuron loss in the spinal cord at the cervical level. Clinically, monomelic amyotrophy is defined ...
  • Modification of transfer RNA levels affects cyclin aggregation and the correct duplication of yeast cells 

    Arias, Loreto; Martínez, Fabián; González, Daniela; Flores Ríos, Rodrigo; Katz, Assaf; Tello, Mario; Moreira, Sandra; Orellana, Omar (Frontiers Media, 2021)
    Codon usage bias (the preferential use of certain synonymous codons (optimal) over others is found at the organism level (intergenomic) within specific genomes (intragenomic) and even in certain genes. Whether it is the ...
  • Enfrentamiento de las infecciones de piel en el adulto 

    Flores, Rodrigo; Villarroel, José Luis; Valenzuela, Fernando (Elsevier, 2021)
    En la actualidad, las infecciones de piel y partes blandas forman parte de un alto porcentaje de las consultas en salud. Estas van desde infecciones leves, donde el manejo se realiza con tratamiento tópico, hasta aquellas ...
  • Safeguarding vaccine production and supply strategies for polio eradication endgame 

    Bandyopadhyay, Ananda S.; O'Ryan Gallardo, Miguel (Elsevier, 2021)
  • Green space exposure association with type 2 diabetes mellitus, physical activity, and obesity: a systematic review 

    Fuente Álvarez, Felipe de la; Saldías Fernández, María Angélica; Cubillos, Camila; Mery Muñoz, Gabirela; Carvajal Pizarro, Daniela; Bowen, Martín; Bertoglia Arredondo, María Paz (MDPI, 2021)
    Type 2 diabetes mellitus (T2DM) is a public health challenge that must be addressed considering the large number of risk factors involved in its appearance. Some environmental risk factors are currently described as ...
  • Efectos demográficos, clínicos y biológicos de la postergación de la maternidad 

    Fuentes, Ariel; Sequeira Alvarado, Karina; Tapia Pizarro, Alejandro (Elsevier, 2021)
    This article analyzes the effects of the postponement of maternity in three areas: i) demographic, ii) clinical and perinatological and iii) biological. Of course, the existing demographic literature comes primarily ...
  • Description of the position and performance of an echocardiogram by subcostal view during the prone position in a patient with severe pneumonia caused by COVID-19 

    Castillo Gordillo, César del; Yáñez Vidal, Francisca; Begazo Gonzáles, Arnulfo; Alfaro Díaz, Mario (BMJ, 2020)
  • Manifiesto Florence para unos mejores cuidados basados en la evidencia 

    García Alamino, Josep Ma.; Escuriet Peiró, Ramón; Fabrellas Padres, Nuria; Fernández Garrido, Julio; Sanz Moncusi, Miquel; Binfa Esbir, Lorena; Román Abal, Eva; Díaz Herrera, Miguel; Fernández Sarmiento, Juan Manuel; López Saludes, María; González Gálvez, Pilar; Canet Vélez, Olga; López Cano, Manuel (Ediciones Rol, 2020)
    It can be said that nurses have not always used a judicious, conscious and explicit system to apply care or make clinical decisions, based on the most reliable and up-to-date scientific knowledge. Considering the current ...
  • Getting intimate: lysosomes and ER rendezvous to control autophagy 

    Pihán, Philippe; Hetz Flores, Claudio (Elsevier, 2020)
    The endoplasmic reticulum (ER) is the source of lysosomal calcium. The finding that the protein TMBIM6 -a putative ER calcium channel and cell death regulator-promotes calcium transfer from the ER to lysosomes to induce ...
  • Maternal sepsis 

    Escobar, María Fernanda; Echavarría, María Paula; Zambrano, María Andrea; Ramos, Isabella; Kusanovic, Juan Pedro (Elsevier, 2020)
    Maternal sepsis is "a life-threatening condition defined as an organ dysfunction caused by an infection during pregnancy, delivery, puerperium, or after an abortion," with the potential to save millions of lives if a proper ...
  • Maximizing the potential of trauma registries in low-income and middle-income countries 

    Rosenkrantz, Leah; Schuurman, Nadine; Arenas, Claudia; Nicol, Andrew; Hameed, Morad S. (BMJ, 2020)
    Injury is a major global health issue, resulting in millions of deaths every year. For decades, trauma registries have been used in wealthier countries for injury surveillance and clinical governance, but their adoption ...
  • Dolor lumbar: revisión y evidencia de tratamiento 

    Santos, Cristián; Donoso, Rodrigo; Ganga Villagrán, Marcos; Eugenin, Óscar; Lira, Fernando; Santelices, Juan Pablo (Elsevier, 2020)
    El dolor lumbar corresponde a uno de los síntomas más prevalentes en la humanidad, siendo la segunda causa más frecuente de atención médica a nivel mundial. Existen diversos enfoques de diagnóstico y tratamiento para dolor ...
  • Damage Control in Penetrating Liver Trauma: fear of the Unknown 

    Ordóñez, Carlos A.; Parra, Michael W.; Millán, Mauricio; Caicedo, Yaset; Guzmán Rodríguez, Mónica; Padilla, Natalia; Salamea Molina, Juan Carlos; García, Alberto; González Hadad, Adolfo; Fernando Pino, Luis; Herrera, Mario Alain; Rodríguez Holguín, Fernando; Serna, José; Salcedo, Alexander; Aristizábal, Gonzalo; Orlas, Claudia; Ferrada, Ricardo; Scalea, Thomas; Ivatury, Rao (Médica Valle, Colombia, 2020)
    The liver is the most commonly affected solid organ in cases of abdominal trauma. Management of penetrating liver trauma is a challenge for surgeons but with the introduction of the concept of damage control surgery ...
  • Escherichia coli HS and enterotoxigenic escherichia coli hinder stress granule assembly 

    Velásquez Salinas, Felipe; Marín Rojas, Josefina; Soto Rifo, Ricardo; Torres, Alexia; Canto Fuentes, Felipe del; Valiente Echeverría, Fernando (MDPI, 2021)
    Escherichia coli, one of the most abundant bacterial species in the human gut microbiota, has developed a mutualistic relationship with its host, regulating immunological responses. In contrast, enterotoxigenic E. coli ...
  • RNA Helicase DDX3: A Double-Edged Sword for Viral Replication and Immune Signaling 

    Hernández Díaz, Tomás; Valiente Echeverría, Fernando; Soto Rifo, Ricardo (MDPI, 2021)
    DDX3 is a cellular ATP-dependent RNA helicase involved in different aspects of RNA metabolism ranging from transcription to translation and therefore, DDX3 participates in the regulation of key cellular processes including ...
  • Resection of an aggressive nodular fasciitis of the mandible in an infant girl 

    Catoia Fonseca, Bruno; Velozo Papez, Luis; Barros Becker, María Emilia; Paulós Parot, María Angélica; Aldunate Riedemann, María Margarita; Muñoz Torres, Carla (Elsevier, 2021)
    Nodular fascitis is a benign pseudosarcomatous self-limited fibroblastic and myofibroblastic cell neoplasia that occasionally can be found in pediatric patients, in who head and neck is reported to be a common location. ...

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