Browsing by Author "10e9c357-7fe2-4fe1-9c20-b50dda97fc8b"

Now showing items 1-3 of 3

    • Nuclear accumulation of beta-catenin is associated with endosomal sequestration of the destruction complex ... 
      Reyes Rojas, Montserrat; Peña Oyarzún, Daniel; Silva, Patricio; Venegas, Sebastián; Criollo Céspedes, Alfredo; Torres Gómez, Vicente (Wiley, 2020)
      Potentially malignant lesions, commonly referred to as dysplasia, are associated with malignant transformation by mechanisms that remain unclear. We recently reported that increased Wnt secretion promotes the nuclear ...
    • The RabGEF ALS2 is a hypoxia inducible target associated with the acquisition of aggressive traits in tumor cells 
      Rivas, Solange; Silva, Patricio; Reyes Rojas, Montserrat; Sepúlveda, Hugo; Solano, Luis; Acuña, Juan; Guerrero, Marisol; Varas Godoy, Manuel; Quest, Andrew F. G.; Montecino, Martín; Torres Gómez, Vicente (Nature, 2020)
      Tumor hypoxia and the hypoxia inducible factor-1, HIF-1, play critical roles in cancer progression and metastasis. We previously showed that hypoxia activates the endosomal GTPase Rab5, leading to tumor cell migration and ...
    • The salivary peptide histatin-1 promotes endothelial cell adhesion, migration, and angiogenesis 
      Torres, Pedro; Díaz Jara, Jorge; Arce, Maximiliano; Silva, Patricio; Mendoza, Pablo; Lois, Pablo; Molina Berríos, Alfredo Enrique; Owen, Gareth I.; Palma Alvarado, Verónica; Torres Gómez, Vicente (Federation of American Societies for Experimental Biology, 2017)
      Saliva is a key factor that contributes to the high efficiency of wound healing in the oral mucosa. This is not only attributed to physical cues but also to the presence of specific peptides in the saliva, such as histatins. ...