Browsing by Subject "Autophagy"

Now showing items 1-6 of 6

    • Aggregatibacter actinomycetemcomitans Induces Autophagy in Human Junctional Epithelium Keratinocytes 
      Vicencio, Emiliano; Cordero, Esteban M.; Cortés, Bastián I.; Palominos, Sebastián; Parra, Pedro; Mella, Tania; Henrríquez, Constanza; Salazar, Nelda; Monasterio Ocares, Gustavo; Cafferata, Emilio A.; Murgas, Paola; Vernal Astudillo, Rolando; Cortez, Cristian (MDPI, 2020)
      The adverse environmental conditions found in the periodontium during periodontitis pathogenesis stimulate local autophagy responses, mainly due to a continuous inflammatory response against the dysbiotic subgingival ...
    • Autophagy and its impact on neurodegenerative diseases: new roles for TDP-43 and C9orf72 
      Budini, Mauricio; Buratti, Emanuele; Morselli, Eugenia; Criollo Céspedes, Alfredo (Frontiers, 2017-05-30)
      Autophagy is a catabolic mechanism where intracellular material is degraded by vesicular structures called autophagolysosomes. Autophagy is necessary to maintain the normal function of the central nervous system (CNS), ...
    • Autophagy in aging-related oral diseases 
      Peña Oyarzún, Daniel; San Martin, Carla; Hernández Cáceres, María Paz; Lavandero González, Sergio Alejandro; Morselli, Eugenia; Budini Budini, Mauricio Fernando; Burgos, Patricia V.; Criollo Céspedes, Alfredo Guillermo (Frontiers Media, 2022)
      Autophagy is an intracellular degradation mechanism that allows recycling of organelles and macromolecules. Autophagic function increases metabolite availability modulating metabolic pathways, differentiation and cell ...
    • Chaperone mediated autophagy substrates and components in cancer 
      Ríos, Javiera; Sequeida, Álvaro; Albornoz, Amelina; Budini, Mauricio Fernando (Frontiers Media SA, 2021)
      Chaperone-mediated autophagy (CMA) represents a specific way of lysosomal protein degradation and contrary to macro and microautophagy is independent of vesicles formation. The role of CMA in different physiopathological ...
    • Limited heme oxygenase contribution to modulating the severity of salmonella enterica serovar typhimurium infection 
      Sebastián, Valentina P.; Moreno Tapia, Daniela; Melo González, Felipe; Hernández Cáceres, María Paz; Salazar, Geraldyne A.; Pardo Roa, Catalina; Farías, Mónica A.; Vallejos, Omar P.; Schultz, Bárbara M.; Morselli, Eugenia; Álvarez Lobos, Manuel M.; González, Pablo A.; Kalergis, Alexis M.; Bueno, Susan M. (MDPI, 2022)
      An important virulence trait of Salmonella enterica serovar Typhimurium (S. Typhimurium) is the ability to avoid the host immune response, generating systemic and persistent infections. Host cells play a crucial role in ...
    • PKD2/polycystin-2 induces autophagy by forming a complex with BECN1 
      Peña Oyarzún, Daniel; Rodríguez Peña, Marcelo; Burgos Bravo, Francesca; Vergara, Ángelo; Kretschmar Montecinos, Catalina; Sotomayor Flores, Cristián; Ramírez Sarmiento, César A.; De Smedt, Humbert; Reyes Rojas, Montserrat; Pérez, William; Torres Gómez, Vicente; Morselli, Eugenia; Altamirano, Francisco; Wilson, Christian; Hill, Joseph A.; Lavandero González, Sergio; Criollo Céspedes, Alfredo (Taylor & Francis, 2020)
      Macroautophagy/autophagy is an intracellular process involved in the breakdown of macromolecules and organelles. Recent studies have shown that PKD2/PC2/TRPP2 (polycystin 2, transient receptor potential cation channel), a ...