Now showing items 1-19 of 19

    • Monasterio, Gustavo; Castillo, Francisca; Ibarra, Juan; Guevara, José; Rojas, Leticia; Alvarez, Carla; Fernández, Baltasar; Agüero, Amaru; Betancur, Daniel; Vernal Astudillo, Rolando (Wiley-Blackwell, 2018)
      BACKGROUND: Aggregatibacter actinomycetemcomitans expresses several virulence factors that may contribute to the pathogenesis of periodontitis. Based on the antigenicity of the O-polysaccharide component of the ...
    • López, Néstor; Jara, Lilian; Valenzuela, Carlos (2005)
      Background: Several studies have investigated genetic polymorphisms for cytokines as potential genetic markers for periodontitis. Some studies have found that interleukin (IL)-1A and IL-1B polymorphisms are associated with ...
    • Pujol, Myriam; Borie Polanco, Consuelo; Montoya, María; Ferreira, Arturo; Vernal Astudillo, Rolando (Elsevier, 2019)
      Brucella canis is a small intracellular Gram-negative bacterium that frequently leads to chronic infections highly resistant to antibiotic therapy in dogs. Also, it causes mild human brucellosis compared to other zoonotic ...
    • Cavalla Ruiz, Franco; Letra, A.; Silva, R. M.; Garlet, G. P. (SAGE, 2020)
      Periodontal and periapical lesions are infectious inflammatory osteolitytic conditions in which a complex inflammatory immune response mediates bone destruction. However, the uncertainty of a lesion's progressive or stable ...
    • Vernal Astudillo, Rolando; León, Rubén; Silva, Augusto; Van Winkelhoff, Arie; García Sanz, José; Sanz, Mariano (2009)
      Aim: Capsular polysaccharides play an important role in the virulence of Grampositive and Gram-negative bacteria. In Porphyromonas gingivalis, six serotypes have been described based on capsular antigenicity and its ...
    • Sansores España, Luis; Morales Lara, Francisca; Arriola Pacheco, Fabio; Astorga, Jessica; Paula Lima, Andrea; Carrillo Ávila, Arelly; Melgar Rodríguez, Samanta; Martínez Aguilar, Víctor; Díaz Zúñiga, Jaime (Universidad Costa Rica, Facultad Odontología, 2022)
      Periodontitis is a low-grade inflammatory disease caused by a subgingival dysbiotic microbiota. Multiple studies have determined the higher prevalence of tooth loss and poor oral hygiene in patients with Alzheimer's disease ...
    • Monasterio, Gustavo; Guevara, José; Ibarra, Juan; Castillo, Francisca; Díaz Zúñiga, Jaime; Alvarez, Carla; Cafferata, Emilio; Vernal Astudillo, Rolando (Springer Verlag, 2018)
      Objectives Periodontitis is a chronic inflammatory disease characterized by tooth-supporting tissue destruction, which is elicited by the host’s immune response triggered against periodonto-pathogen bacteria. During ...
    • Navarrete, Mariely; García, Jocelyn; Dutzan Muñoz, Nicolás; Henríquez, Leslie; Puente Piccardo, Javier; Carvajal, Paola; Hernández Ríos, Marcela; Gamonal Aravena, Jorge Antonio (Elsevier, 2014)
      Background: Macrophages account for 5% to 30% of the inflammatory infiltrate in periodontitis and are activated by the classic and alternative pathways. These pathways are identified by indirect markers, among which ...
    • Navarrete, Mariely; García, Jocelyn; Dutzan, Nicolás; Henríquez, Leslie; Puente, Javier; Carvajal, Paola; Hernandez, Marcela; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2014)
      Macrophages account for 5% to 30% of the inflammatory infiltrate in periodontitis and are activated by the classic and alternative pathways. These pathways are identified by indirect markers, among which interferon (IFN)-γ ...
    • López, Néstor; Valenzuela, Carlos; Jara, Lilian (2009)
      Background: Epidemiologic studies have shown an increased frequency, severity, and risk of periodontitis in patients with diabetes. Periodontitis is associated with certain interleukin (IL)-1 gene cluster polymorphisms. ...
    • Dutzan Muñoz, Nicolás; Vernal Astudillo, Rolando; Vaque, Jose; García Sesnich, Jocelyn; Hernandez, Marcela; Abusleme, Loreto; Dezerega, Andrea; Gutkind, J.; Gamonal Aravena, Jorge Antonio (2012)
      Background: Interleukin-21 (IL-21) controls the differentiation of T-helper Th17 cells and induces the production of IL-17 in this T-cell subtype. The aim of this study is to determine the relative expression of IL-21 ...
    • Gamonal Aravena, Jorge Antonio; Acevedo, A.; Bascones, A.; Jorge, O.; Silva, A. (American Academy of Periodontology, 2000)
      Background: Various cytokines have been identified at sites of chronic inflammation such as periodontitis. Cytokines are synthesized in response to bacteria and their products, inducing and maintaining an inflammatory ...
    • Dutzan Muñoz, Nicolás; Rivas, Catalina; García Sesnich, Jocelyn; Henríquez, Leslie; Rivera Escobar, Oriana; Dezerega Piwonka, Andrea; Hernández Ríos, Emma; Silva Steffens, Nora; Aguillón Gutiérrez, Juan Carlos; Puente Piccardo, Javier; Vernal Astudillo, Rolando; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2011-10)
      BACKGROUND: A growing body of evidence suggested that interleukin (IL)-21 enhances the effector phase during T-cell responses. The aim of our study is to determine the levels of IL-21 in periodontal sites from patients ...
    • Cavalla Ruiz, Ian; Osorio Alfaro, Constanza; Paredes, Rodolfo; Valenzuela Pedevila, María Antonieta; García Sesnich, Jocelyn; Sorsa, Timo; Tervahartiala, Taina; Hernández Ríos, Emma (Elsevier, 2015)
      Periodontitis is a highly prevalent infectious disease characterized by the progressive inflammatory destruction of tooth-supporting structures, leading to tooth loss. The underling molecular mechanisms of the disease ...
    • Favaro Trombone, Ana Paula; Cavalla Ruiz, Ian Franco; Varize Silveira, Elcia María; Andreo, Camile Bermejo; Francisconi, Carolina Favaro; Fonseca, Angélica Cristina; Letra, Ariadne; Silva, Renato Menezes; Garlet, Gustavo Pompermaier (2016)
      Increased matrix metalloproteinases (MMPs) activity is a hallmark of periapical granulomas. However, the factors underlying the MMPs expression modulation in healthy and diseased periapical tissues remains to be determined. ...
    • Cafferata Chea, Emilio; Monasterio Ocares, Gustavo; Castillo Franzoy, Francisca; Carvajal Pavez, Paola; Flores Sepúlveda, Guillermo; Díaz Guzmán, Walter; Fuentes del Campo, Aler; Vernal Astudillo, Rolando (Wiley, 2020)
      Objective This study aimed to determine the expression of distinct matrix metalloproteinases, cytokines, and bone resorptive factors in temporomandibular joint osteoarthritis (TMJ-OA) patients and their association with ...
    • Monasterio Ocares, María Carolina; Castillo, F.; García, K.; Álvarez, C.; Rojas, L.; Núñez, C.; Flores, G.; Díaz Guzmán, Walter; Vernal Astudillo, Rolando (2016)
    • Vernal Astudillo, Rolando; Velásquez, E.; Gamonal Aravena, Jorge Antonio (2007)
      Propósito. La osteoartritis temporomandibular es una enfermedad articular degenerativa, caracterizada por la destrucción del cartílago y hueso articular consecutiva a la respuesta inflamatoria e inmune desarrollada. En ...
    • Rojas, Leticia; Melgar Rodríguez, Samanta; Díaz Zúñiga, Jaime; Alvarez, Carla; Monasterio, Gustavo; Rojas, Carolina; Carvajal, Paola; Vernal Astudillo, Rolando (Elsevier Ltd, 2018)
      Objective: In Aggregatibacter actinomycetemcomitans, different serotypes have been described based on LPS antigenicity. Mixed infection with the different A. actinomycetemcomitans serotypes is frequent in periodontitis ...