Browsing by Subject "Immunology"

Now showing items 1-6 of 6

    • ATP Induces IL-1 β Secretion in Neisseria gonorrhoeae-Infected Human Macrophages by a Mechanism Not Related ... 
      Garciá, Killen; Escobar, Gisselle; Mendoza, Pablo; Beltran, Caroll; Pérez, Claudio; Arancibia, Sergio; Vernal Astudillo, Rolando; Rodas, Paula; Acunã-Castillo, Claudio; Escobar, Alejandro (Hindawi Limited, 2016)
      Neisseria gonorrhoeae (Ngo) has developed multiple immune evasion mechanisms involving the innate and adaptive immune responses. Recent findings have reported that Ngo reduces the IL-1𝛽 secretion of infected human ...
    • DL-2-hydroxyisocaproic acid attenuates inflammatory responses in a murine Candida albicans biofilm model 
      Nieminen, M.; Hernández, M.; Novak-Frazer, L.; Kuula, H.; Ramage, G.; Bowyer, P.; Warn, P.; Sorsa, T.; Rautemaa, R. (2014)
      Chronic biofilm infections are often accompanied by a chronic inflammatory response, leading to impaired healing and increased, irreversible damage to host tissues. Biofilm formation is a major virulence factor for Candida ...
    • Interferon-γ, interleukins-6 and -4, and factor XIII-A as indirect markers of the classical and alternative ... 
      Navarrete, Mariely; García, Jocelyn; Dutzan, Nicolás; Henríquez, Leslie; Puente, Javier; Carvajal, Paola; Hernandez, Marcela; Gamonal Aravena, Jorge Antonio (American Academy of Periodontology, 2014)
      Macrophages account for 5% to 30% of the inflammatory infiltrate in periodontitis and are activated by the classic and alternative pathways. These pathways are identified by indirect markers, among which interferon (IFN)-γ ...
    • Lateral flow immunoassay for diagnosis of trypanosoma cruzi infection with high correlation to the ... 
      Houghton, Raymond; Stevens, Yvonne; Hjerrild, Kathryn; Guderian, Jeff; Okamoto, Masahiko; Kabir, Mazbahul; Reed, Steven; Leiby, David; Morrow, W.; Lorca, Myriam; Raychaudhuri, Syamal (2009)
      The incidence of blood donors seropositive for Trypanosoma cruzi in North America has increased with population migration and more rigorous surveillance. The United States, considered nonendemic for T. cruzi, could therefore ...
    • Lipopolysaccharide inhibits the channel activity of the P2X7 receptor 
      Leiva Salcedo, Elías; Coddou, Claudio; Rodríguez, Felipe; Penna, Antonello; López, Ximena; Neira, Tanya; Fernández, Ricardo; Imarai, Mónica; Rios, Miguel; Escobar, Jorge; Montoya, Margarita; Huidobro Toro, Juan; Escobar, Alejandro; Acuña Castillo, Claudio (2011)
      The purinergic P2X7 receptor (P2X7R) plays an important role during the immune response, participating in several events such as cytokine release, apoptosis, and necrosis. The bacterial endotoxin lipopolysaccharide (LPS) ...
    • PGC-1α-dependent mitochondrial adaptation is necessary to sustain IL-2-induced activities in human NK cells 
      Miranda, Dante; Jara, Claudia; Ibañez, Jorge; Ahumada, Viviana; Acuña Castillo, Claudio; Martin, Adrian; Córdova, Alexandra; Montoya, Margarita (Hindawi Publishing Corporation, 2016)
      Human Natural Killer (NK) cells are a specialized heterogeneous subpopulation of lymphocytes involved in antitumor defense reactions. NK cell effector functions are critically dependent on cytokines and metabolic activity. ...