Browsing by Subject "Osteoclast"

Now showing items 1-4 of 4

    • Impact of DBBM fragments on the porosity of the calvarial bone: A pilot study on mice 
      Kuchler, Ulrike; Heimel, Patrick; Staehli, Alexandra; Strauss, Franz Josef; Luza, Bernadette; Gruber, Reinhard (MDPI, 2020)
      Deproteinized bovine bone mineral (DBBM) is brittle and can break into fragments. Here, we examined whether DBBM fragments have an impact on mice calvarial bone during bone augmentation. DBBM was either randomly crushed ...
    • Inhibition of osteolysis and increase of bone formation after local administration of siRNA-targeting RANK ... 
      Córdova Jara, Luis; Trichet, V.; Escriou, V.; Rosset, P.; Amiaud, J.; Battaglia, S.; Charrier, C.; Berreur, M.; Brion, R.; Gouin, F.; Layrolle, P.; Passuti, N.; Heymann, D. (Elsevier, 2015)
      Receptor activator of nuclear factor kappa-B (RANK) and RANK-ligand are relevant targets for the treatment of polyethylene particle-induced osteolysis. This study assessed the local administration of siRNA, targeting ...
    • Proteomic and genomic analysis of acid dentin lysate with focus on TGF-β signaling 
      Nasirzade, Jila; Kargarpour, Zahra; Mitulović, Goran; Strauss Avendaño, Franz Josef; Panahipour, Layla; Schwarz, Frank; Gruber, Reinhard (Nature, 2021)
      Particulate autologous tooth roots are increasingly used for alveolar bone augmentation; however, the proteomic profile of acid dentin lysate and the respective cellular response have not been investigated. Here we show ...
    • Severe compromise of preosteoblasts in a surgical mouse model of bisphosphonate-associated osteonecrosis of the jaw 
      Córdova Jara, Luis Alberto; Guilbaud, Florian; Amiaud, Jerome; Battaglia, Severine; Charrier, Celine; Lezot, Frederic; Piot, Benoit; Redini, Francoise; Heymann, Dominique (2016)
      Objectives: The effect of amino-bisphosphonates on osteoblastic lineage and its potential contribution to the pathogenesis of bisphosphonate-associated osteonecrosis of the jaw (BONJ) remain controversial. We assessed the ...