Now showing items 1-5 of 5

    • Loi, Florence; Córdova Jara, Luis; Zhang, Ruth; Pajarinen, Jukka; Lin, Tzu-hua; Goodman, Stuart B.; Yao, Zhenyu (BioMed Central, 2016)
      Background: Bone formation and remodeling are influenced by the inflammatory state of the local microenvironment. In this regard, macrophages are postulated to play a crucial role in modulating osteogenesis. However, the ...
    • Biguetti, Claudia Cristina; Cavalla, Franco; Silveira, Elcia Varize; Tabanez, André Petenuci; Francisconi, Carolina Favaro; Taga, Rumio; Campanelli, Ana Paula; Trombone, Ana Paula Favaro; Rodrigues, Danieli C.; Garlet, Gustavo Pompermaier (Frontiers Media, 2019)
      The release of the prototypic DAMP High Mobility Group Box 1 (HMGB1) into extracellular environment and its binding to the Receptor for Advanced Glycation End Products (RAGE) has been described to trigger sterile inflammation ...
    • Silva, Nora; Abusleme Ramos, Loreto Andrea; Bravo, Denisse; Dutzan Muñoz, Nicolás; García Sesnich, Jocelyn; Vernal Astudillo, Rolando; Hernández, Marcela; Gamonal Aravena, Jorge Antonio (Univ Sao Paulo Fac Odontologia Bauru, 2015)
      Periodontal diseases usually refer to common inflammatory disorders known as gingivitis and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm, including Porphyromonas gingivalis, ...
    • Amengual Peñafiel, Luis; Córdova Jara, Luis; Jara Sepúlveda, Constanza; Brañes Aroca, Manuel; Marchesani Carrasco, Francisco; Cartes Velásquez, Ricardo (Elsevier, 2021)
      There is a complex interaction between titanium dental implants, bone, and the immune system. Among them, specific immune cells,macrophages play a crucial role in the osseointegration dynamics.Infiltrating macrophages ...
    • González Ouna, Luis Gustavo; Sierra Cristancho, Alfredo José; Rojas Pérez, Carolina Isabel; Cafferata Chea, Emilio Alfredo; Melgar Rodríguez, Samanta Azucena; Cárdenas Gutiérrez, Angélica María; Vernal Astudillo, Rolando Marcelo (International Society on Aging and Disease, USA, 2021)
      Cellular senescence is a biological process triggered in response to time-accumulated DNA damage, which prioritizes cell survival over cell function. Particularly, senescent T lymphocytes can be generated prematurely during ...