Now showing items 1-6 of 6

    • Hernández Ríos, Marcela; Baeza Paredes, Mauricio Enrique; Raisanen, Ismo; Contreras Balbontín, Johanna; Tervahartiala, Taina; Chaparro, Alejandra; Sorsa, Timo; Hernández Ríos, Patricia (MDPI, 2021)
      Periodontitis is a host-mediated bacterial disease that affects the tooth attachment apparatus. Metalloproteinase-8 (MMP-8), a validated biomarker, could aid in clinical diagnosis. This study aimed to evaluate the diagnostic ...
    • Hernandez, M.; Gamonal Aravena, Jorge; Tervahartiala, T.; Mantyla, P.; Rivera, O.; Dezerega, A.; Dutzan, N.; Sorsa, T. (2010)
      Backround: Matrix metalloproteinase (MMP)-8 is a central mediator in chronic periodontitis. MMP-8 can be activated by the cooperative action of other MMPs such as MMP-14, reactive oxygen species, and microbial proteases. ...
    • Cavalla Ruiz, Franco; Letra, A.; Silva, R. M.; Garlet, G. P. (SAGE, 2020)
      Periodontal and periapical lesions are infectious inflammatory osteolitytic conditions in which a complex inflammatory immune response mediates bone destruction. However, the uncertainty of a lesion's progressive or stable ...
    • Magrin, Gabriel Leonardo; Strauss Avendaño, Franz; Magalhães Benfatti, César Augusto; Cople Maia, Lucianne; Gruber, Reinhard (MDPI, 2020)
      Short-chain fatty acids (SCFA), bacterial metabolites released from dental biofilm, are supposed to target the oral epithelium. There is, however, no consensus on how SCFA affect the oral epithelial cells. The objective ...
    • Smith, Patricio; Muñoz, Valeria; Collados, Lucía; Oyarzún, Alejandro (2004)
      BACKGROUND AND OBJECTIVE: As the periodontal lesion develops, the junctional epithelium migrates apically in conjunction with the dissolution of the most coronal Sharpey's fibers. Because matrix metalloproteinase-9 (MMP-9) ...
    • Metcalfe, Sarah; Anselmi, Natalie; Escobar Álvarez, Alejandro Felipe; Visser, Michelle B.; Kay, Jason G. (Frontiers Media, 2022)
      The oral cavity is a complex environment constantly exposed to antigens from food and the oral microbiota. Innate immune cells play an essential role in maintaining health and homeostasis in the oral environment. However, ...