Browsing by Subject "Polymorphism"

Now showing items 1-2 of 2

    • MMP1-1607 polymorphism increases the risk for periapical lesion development through the upregulation MMP-1 ... 
      Favaro Trombone, Ana Paula; Cavalla Ruiz, Ian Franco; Varize Silveira, Elcia María; Andreo, Camile Bermejo; Francisconi, Carolina Favaro; Fonseca, Angélica Cristina; Letra, Ariadne; Silva, Renato Menezes; Garlet, Gustavo Pompermaier (2016)
      Increased matrix metalloproteinases (MMPs) activity is a hallmark of periapical granulomas. However, the factors underlying the MMPs expression modulation in healthy and diseased periapical tissues remains to be determined. ...
    • P2X7 receptor is essential for cross-dressing of bone marrow-derived dendritic cells 
      Barrera Ávalos, Carlos; Briceño, Pedro; Valdés, Daniel; Imarai, Mónica; Leiva Salcedo, Elías; Rojo, Leonel E.; Milla, Luis A.; Huidobro Toro, Juan Pablo; Robles Planells, Claudia; Escobar Álvarez, Alejandro; Di Virgilio, Francesco; Morón, Gabriel; Sauma Mahaluf, Daniela Macarena; Acuña Castillo, Claudio (Cell, 2021)
      T cell activation requires the processing and presentation of antigenic peptides in the context of a major histocompatibility complex (MHC complex). Cross -dressing is a non-conventional antigen presentation mechanism, ...